肟的立体选择性合成概述

Introduction to the Stereoselective Synthesis of Oximes

立体化学纯的肟被广泛应用于有机合成、药物、食品添加剂等领域。传统方法合成肟的立体选择性取决于底物取代基的空间位阻,其立体选择性合成一直是有机合成领域的难点与挑战。本文简要介绍了立体选择性合成肟的新方法和技术的研究进展。本文的内容来源于基础有机化学,将此内容融入到教学中可以拓展学生的视野,也有助于激发学生发现和解决难题的兴趣。

Stereoselectively pure oximes play a pivotal role in organic synthesis,pharmaceuticals,and as food additives.Traditional synthesis methods rely heavily on the steric hindrance of substrate substituents to achieve oxime stereoselectivity,presenting a significant challenge in organic synthesis.This article offers a concise overview of the latest advancements in techniques and methods for stereoselective oxime synthesis.The insights presented herein are rooted in fundamental organic chemistry.Introducing these concepts into academic curriculum can broaden student perspectives and ignite their enthusiasm for problem discovery and resolution.