期刊文献+

鸭瘟病毒gJ蛋白生物信息学分析

Bioinformatics Analysis of gJ Protein of Duck Plague Virus
下载PDF
导出
摘要 鸭瘟病毒是一种可引起鸭急性、热性、败血性传染病的病毒。gJ蛋白是鸭瘟病毒囊膜蛋白的一种,该文利用生物信息学方法对gJ蛋白进行分析,结果表明,该蛋白由539个氨基酸组成,具有较好的稳定性;有1个α-跨膜螺旋区,有1个信号肽位点;预测了gJ蛋白的二级结构,分析其有52个磷酸化位点,7个糖基化位点,有18个B细胞抗原表位,14个较强的T细胞抗原表位。该研究为进一步研究gJ蛋白的结构特性和免疫功能提供理论依据。 Duck plague virus can cause acute,febrile,and septic infectious diseases in ducks.The gJ protein is a type of envelope protein of duck plague virus.This article analyzed the gJ protein using bioinformatics methods.The results showed that the protein is composed of 539 amino acids with a good stability.There are oneα-transmembrane helical region and one signal peptide site.The secondary structure of gJ protein was predicted.The protein contains 52 phosphorylation sites,7 glycosylation sites,18 B cell antigen epitopes,and 14 strong T cell antigen epitopesin.This study provides a theoretical basis for further studying the structural characteristics and immune function of gJ protein.
作者 李方杰 王宵 李美荃 董翠莲 LI Fangjie;WANG Xiao;LI Meiquan;DONG Cuilian(College of Agriculture and Life Sciences,Kunming University,Kunming Yunnan 650214,China)
出处 《现代畜牧科技》 2024年第2期6-8,共3页 Modern Animal Husbandry Science & Technology
基金 云南省教育厅科学研究基金项目(2019J0568) 云南省地方本科高校(部分)基础研究联合专项资金项目(20201BA070001-207) 昆明学院引进人才科研项目(YJL19007)。
关键词 鸭瘟病毒 gJ蛋白 生物信息学 duck plague virus gJ protein bioinformatics
  • 相关文献

参考文献3

二级参考文献11

  • 1黄引贤.鸭瘟病毒的研究.华南农学院学报,1980,1(1):21-36.
  • 2SaifYM.禽病学[M].11版.高福,苏敬良,索勋,译.北京:中国农业出版社,2004:520-528.
  • 3Davison A J, Eberle R, Ehlers B, etal. The order Herpesvi- rales. Archives of Virology [J]. 2009, 154: 171-177.
  • 4Li Y, Huang B, Ma X, et al. Molecular characterization of the genome of duck enteritis virus [J]. Virology, 2009, 391, 151-161.
  • 5Wang J, HOper D, Beer M, et al. Complete genome sequence of virulent duck enteritis virus (DEV) strain 2085 and compar- ison with genome sequences of virulent and attenuated DEV stralns[J]. Virus Research, 2011, 160, 316-325.
  • 6Plummer P J, Alefantis T, Kaplan S, etal. Detection of duck enteritis virus by polymerase chain reaction [J]. Avian Disea- ses, 1998, 42, 554-564.
  • 7Brockmeier S I., Lager K M, Tartaglia J, etal. Vaccination of pigs against pseudorabies with highly attenuated vaccinia (NY VAC) recombinant viruses [J]. Veterinary Microbiology, 1993, 38, 41-58.
  • 8Riviere M, Tartaglia J, Perkus M E, etal. Protection of mice and swine from pseudorabies virus conferred by vaccinia virus- based recombinants [J]. Journal of Virology, 1992, 66, 3424- 3434.
  • 9NazarianK, Lee L F, Yanagida N, et al. Protection against Marcks disease by a fowlpox virus recombinant expressing the glycoprotein B of Marek's disease virus [J]. Journal of Virolo gy, 1992, 66, 1409-1413.
  • 10NauwynekK H J. Functional aspects of Aujeszky's disease (pseudorabies) viral proteins with relation to invasion, viru- lence and immunogenicity[J]. Veterinary Microbiology, 1997, 55, 3-11.

共引文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部