摘要
雾化吸入疗法(aerosol inhalation therapy)是利用高速氧气气流或专门的雾化装置(雾化器),使药液形成雾状,再由呼吸道吸入,达到治疗呼吸道感染疾病,消除炎症和呼吸道水肿,以及解痉、稀化痰液、帮助祛痰的作用,其在人类呼吸系统疾病管理中起着越来越重要的作用。对呼吸系统疾病患儿雾化吸入治疗中,雾化器类型选择,对其临床疗效至关重要。目前临床常用于治疗呼吸系统疾病患儿的雾化器类型包括超声雾化器(UN)、压力射流雾化器(JN)与振动筛网雾化器(VMN)3种。基于不同工作原理的雾化器中,VMN的优势最为明显。笔者拟就雾化吸入疗法的优势和劣势,UN及JN的优、缺点与适用范围,VMN的优势及其应用等的最新研究进展进行阐述,旨在为临床对呼吸系统疾病患儿治疗选用更合适的雾化器提供参考。
Aerosol inhalation therapy utilizes high-speed oxygen airflow or nebulizers to transform liquid medicine into a mist,which is then inhaled through the respiratory tract to treat respiratory infections,eliminate inflammation and respiratory edema,and achieve spasm relief,sputum dilution,and help with sputum expulsion.It plays an increasingly important role in management of human respiratory system diseases.The selection of nebulizer type is crucial for clinical efficacy of aerosol therapy in children with respiratory system diseases.Currently,the nebulizers commonly used in clinical treatment for children with respiratory system diseases include ultrasonic nebulizer(UN),jet nebulizer(JN),and vibrating mesh nebulizer(VMN).Among atomizers based on different working principles,VMN has the most obvious advantages.The author intends to elaborate on the advantages and disadvantages of aerosol inhalation therapy,the advantages,disadvantages,and scope of application of UN and JN,as well as the advantages and applications of VMN,in order to provide reference for clinical selection of more suitable nebulizers for treatment of children with respiratory system diseases.
作者
胡贵容
王伟
蔡强
谢亮
刘瀚旻
Hu Guirong;Wang Wei;Cai Qiang;Xie Liang;Liu Hanmin(Department of Pediatric Respiratory Immunology,Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University),Ministry of Education,West China Second University Hospital,Sichuan University,NHC Key Laboratory of Chronobiology(Sichuan University),The Joint Laboratory for Lung Development and Related Diseases of West China Second University Hospital(Sichuan University)and School of Life Sciences of Fudan University,Chengdu 610041,Sichuan Province,China;Department of Pediatrics,the Second People′s Hospital of Yibin,Yibin 644000,Sichuan Province,China)
出处
《中华妇幼临床医学杂志(电子版)》
CAS
2023年第6期636-642,共7页
Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)
基金
国家自然科学基金区域创新发展联合基金项目(U21A20333)
四川省科技厅重点研发项目(2019YFS0037)
成都市科技局重大科技应用示范项目(2019-YF09-00087-SN)。
关键词
雾化器和汽化器
呼吸系统疾病
雾化吸入疗法
气溶胶
超声雾化器
压力射流雾化器
振动筛网雾化器
雾化
儿童
Nebulizers and vaporizers
Respiratory system diseases
Nebulization inhalation therapy
Aerosol
Ultrasonic nebulizers
Jet nebulizers
Vibrating mesh nebulizers
Nebulization
Child