基于CiteSpace软件的冠状动脉支架内再狭窄研究可视化分析

Studies on in-stent restenosis of coronary artery based on CiteSpace software:a visual analysis

目的分析国内外关于冠状动脉支架内再狭窄(ISR)的研究热点及前沿。方法用CiteSpace软件分别从发文国家、机构、作者和高频关键词等方面对中国知网及Web of Science数据库近20年发表的ISR相关论文进行可视化分析。结果共纳入2940篇中文文献及9611篇英文文献。中文文献发文机构以医院心内科为主,合作关系疏散。美国发文量最多,与其他国家合作意愿最强,与德国合作最紧密。中文文献显示,冠状动脉粥样硬化性心脏病、支架置入术、介入治疗、再狭窄率、危险因素、糖尿病患者、抗血小板治疗、药物涂层支架是该领域的研究热点。英文文献显示,热点主题包括药物洗脱支架、经皮冠状动脉介入治疗(PCI)、冠状动脉粥样硬化性心脏病(冠心病)、平滑肌细胞、光学相干断层扫描、支架内血栓、血管内超声、裸金属支架、糖尿病、急性心肌梗死等。结论国内外研究者对ISR的关注点不完全相同,国内的相关研究以临床实际应用及探索危险因素为主,国外则在关注ISR的临床诊治的同时也关注了腔内影像学对ISR的指导策略,并进行基础研究来探索ISR背后机制。

Objective To analyze the hotspots and frontiers of coronary in-stent restenosis(ISR)at home and abroad.Methods The research papers related to ISR published in CNKI and Web of Science for resent 20 y were visually analyzed with keywords of country,institution,author and high-frequency keywords by using CiteSpace software.Results There were totally 2940 Chinese literatures and 9611 English literatures included.The publishing institutions of Chinese literatures were mainly the departments of cardiology in hospitals,and there was an evacuated cooperation among these hospitals.The United States had the largest volume of articles published,and had the strongest cooperative willingness with other countries,especially with a most closely cooperation with Germany.The results of analysis on Chinese literatures showed that coronary heart disease(CHD),stent implantation,interventional therapy,restenosis rate,risk factors,diabetic patients,antiplatelet therapy and drug-coated stents were the research hotspots in this field.The results of analysis on English literatures showed that the hot topics included drug-eluting stents,PCI,CHD,smooth muscle cells,optical coherence tomography(OCT),in-stent thrombosis,intravascular ultrasound(IVUS),bare metal stents,diabetes and acute myocardial infarction(AMI).Conclusion The focus on ISR is different in domestic and foreign researchers.The related researches are mainly clinical application and risk factor investigation in China,and foreign countries pay more attention to the clinical diagnosis and treatment of ISR,guiding strategy of intracavitary imaging to ISR and basic studies on mechanism behind ISR.