miR-192-5p在恶性肿瘤中作用机制的研究进展

Research progress in the mechanism of miR-192-5p in malignant tumors

恶性肿瘤是威胁人类健康的常见疾病,其治疗也是加重社会经济负担的主要因素之一。恶性肿瘤患者的死亡率高,预后极差。因此,如何提高恶性肿瘤患者的生存率、改善预后至关重要。miRNA是一类小的非编码RNA,通过参与基因表达的转录后调控,在肿瘤细胞的增殖、分化、迁移和凋亡等过程中发挥重要作用。近年来,人们逐渐开始研究miR-192-5p在恶性肿瘤中的表达及作用,本文将对miR-192-5p在不同恶性肿瘤中作用机制的研究进展进行综述。

Malignant tumors is one of the main threats to human health,and their treatment is also one of the main factors that increase the socio-economic burden.Patients with malignant tumors have a high mortality and extremely poor prognosis.Therefore,it is crucial to improve the survival rate and prognosis of patients with malignant tumors.miRNAs are a class of small non-coding RNAs,which play an important role in the proliferation,differentiation,migration,and apoptosis of tumor cells by participating in the post-transcriptional regulation of gene expression.In recent years,researchers have gradually begun to study the expression and role of miR-192-5p in malignant tumors.This paper will review the research progress of miR-192-5p mechanism in different malignant tumors.