新型冠状病毒感染相关细菌真菌感染特点及管理现状

Progress and characteristics of COVID-19 associated bacterial and fungal infections

在新型冠状病毒感染(COVID-19)全球大流行的背景下,合并细菌真菌感染的报道持续增加,成为导致COVID-19患者死亡的重要原因之一。COVID-19合并的细菌感染较大流行前出现更多的耐药菌,合并的真菌感染以曲霉菌、念珠菌及毛霉菌多见,给COVID-19疾病控制带来极大困难。本文对COVID-19相关细菌真菌感染现状及处理原则做一述评,目的在于加强临床医生对COVID-19相关细菌真菌感染的重视,为进一步规范抗菌药物治疗与管理提供参考。

During the global pandemic of novel coronavirus infection(COVID-19),an increasing number of bacterial and fungal infections have been reported,becoming one of the important causes of death from COVID-19.Compared with before the pandemic,there are more antimicrobial resistance bacteria in COVID-19 associated bacterial infections,and Aspergillus,candida and mucor are more common in COVID-19 associated fungal infections,which brings great challenges to COVID-19 disease control.In this paper,progress and characteristics of COVID-19 associated bacterial and fungal infections are reviewed to strengthen the clinical attention to COVID-19 associated bacterial and fungal infections and provide reference for further standardizating antimicrobial treatment and management.