基于CiteSpace癌症经济毒性研究可视化分析

Visualization analysis of financial toxicity of cancer based on CiteSpace

目的基于CiteSpace对癌症经济毒性领域的研究文献进行可视化分析。方法以癌症和经济毒性的中英文形式为主题和关键词,2012年1月—2023年7月为时间限制,Web of Science(WOS)核心合集和中国知网(CNKI)数据库作为检索对象,利用CiteSpace对文献发文数量趋势、机构、关键词聚类、关键词时间演化、关键词突现等进行知识图谱的可视化分析。结果共纳入中文文献143篇、英文文献898篇,癌症经济毒性主题文献发文数量呈波动上升趋势;英文文献中发文量和影响力最大的机构是哈佛大学;排名前3的高频关键词为经济毒性、生活质量、照护;关键词聚类共形成10个聚类,前3个聚类为经济毒性、住院费用、肺癌;时间线图显示更多的关注逐渐变为经济毒性的干预措施;关键词突现分析显示,强度较高的关键词有经济负担、乳腺癌、花费、结直肠癌等。中文文献中发文量和影响力最大的机构是山东大学,排名前3的高频关键词为影响因素、癌症、经济负担;关键词聚类共形成11个聚类,前3个聚类包括癌症幸存者、健康差异、经济毒性;时间线图显示经济毒性的研究尚处于影响因素研究阶段;关键词突现分析显示,强度较高的关键词有食管癌、癌痛、恶性肿瘤等。结论2012—2023年,癌症经济毒性相关中英文研究呈现数量增多且范围扩宽的趋势,癌症经济毒性受到越来越多的重视,国内对癌症经济毒性的研究也在逐渐增多,但是研究仍然处于疾病的某个阶段,相关研究深度不足,探寻适合我国国情的癌症经济毒性干预研究将会是未来重要的研究方向。

Objective To visually analyze the literature in the field of financial toxicity of cancer based on CiteSpace.Methods The topics and keywords of cancer and financial toxicity in Chinese and English were selected.The time limit was from January 2012 to July 2023.The core collection of Web of Science(WOS)and CNKI database were used as search objects.CiteSpace was used to visualize the knowledge graph of the number trend,organization,keyword clustering,keyword time evolution,keyword emergence,etc.Results A total of 143 literatures in Chinese and 898 lit⁃eratures in English were included.The number of literatures on economic toxicity of cancer showed an increasing trend.The institution with the largest number of publications and influence in English literature is Harvard University.The top 3 high-frequency keywords were economic toxicity,quality of life,care.A total of 10 clusters were formed,and the first three clusters were financial toxicity,hospitalization cost,and lung cancer.The time graph shows a growing focus on eco⁃nomically toxic interventions.Keyword emergence analysis showed that the keywords with high intensity were economic burden,breast cancer,cost,colorectal cancer and so on.The institution with the largest number of publications and influ⁃ence in Chinese literature was Shandong University,and the top 3 high-frequency keywords were influencing factors,can⁃cer and economic burden.A total of 11 clusters were formed,and the first three clusters included cancer survivors,health disparities,and financial toxicity.The time chart showed that the study of financial toxicity was still in the stage of influ⁃encing factors.The keyword emergent analysis showed that the key words with high intensity were esophageal cancer,can⁃cer pain,malignant tumor,etc.Conclusions From 2012 to 2023,the number of Chinese and English studies on financial toxicity of cancer is increasing and the scope is expanding.More and more attention has been paid to financial toxicity of cancer,and the domestic research on financial toxicity of cancer is also increasing,but the research is still at a certain stage of the disease,and the depth of relevant studies is insufficient.It will be an important research direction in the future to explore the financial toxicity intervention of cancer suitable for China's national conditions.