浓缩生长因子在整形外科中的应用进展

Progress in the application of CGF in plastic surgery

近年来血小板制品备受关注,其优势是无毒、无免疫原性,制备成本低。浓缩生长因子是一种富含多种纤维蛋白及生长因子的第三代血小板聚集体。具有促进细胞增殖、分化、趋化和血管化,促进缺陷修复和再生等优点,目前已广泛应用于临床。CGF作为新一代血小板衍生物,部分作用机制尚不明确。笔者总结了CGF在鼻整形术后修复、面部年轻化、雄激素脱发的治疗、神经损伤的修复以及创面的修复机制及临床应用。

In recent years,platelet products have attracted much attention because of their non-toxicity,non-immunogenicity,and low preparation cost.Concentrated growth factor is a third-generation platelet aggregate rich in a variety of fifibrin and growth factors.It has the advantages of promoting cell proliferation,difffferentiation,chemotaxis and vascularization,promoting defect repair and regeneration,and has been widely used in clinical practice.As a new generation of platelet derivatives,the mechanism of action of CGF is still unclear.This article summarizes the mechanism and clinical application of CGF in rhinoplasty repair,facial rejuvenation,androgen alopecia treatment,nerve injury repair,and wound repair.