低分子肝素联合气压疗法在腹腔镜子宫肌瘤剥除术后恢复中应用效果观察

Observation on the Application Effects of Low Molecular Weight Heparin Combined with Pneumatic Therapy in the Recovery of Laparoscopic Uterine Fibroid Removal Surgery

目的:探讨低分子肝素联合气压疗法对腹腔镜子宫肌瘤剥除术患者凝血指标及下肢深静脉血栓形成(DVT)的预防效果。方法:选取2020年6月至2023年6月于安阳市妇幼保健院行腹腔镜子宫肌瘤剥除术治疗的104例患者为研究对象,按照治疗方案不同分为对照组和观察组各52例。对照组术后给予气压疗法治疗,观察组在此基础上加用低分子肝素治疗。两组均维持治疗7 d。比较两组手术相关指标、下肢深静脉血栓发生率、凝血指标、疼痛程度和生活质量。结果:观察组术后出血量少于对照组,住院时间短于对照组,DVT发生率低于对照组(P<0.05);观察组凝血指标优于对照组(P<0.05);两组D-二聚体比较,差异无统计学意义(P>0.05);术后1 d、3 d、5 d、7 d,观察组疼痛评分均低于对照组(P<0.05);观察组生活质量评分高于对照组(P<0.05)。结论:低分子肝素联合气压疗法可有效降低腹腔镜子宫肌瘤剥除术患者术后DVT发生率,改善患者凝血功能,促进患者较快康复。

Objective:To explore the preventive effects of low molecular weight heparin combined with pneumatic therapy on coagulation indicators and lower limb deep vein thrombosis(DVT)in patients undergoing laparoscopic myomectomy.Method:104 Patients who underwent laparoscopic myomectomy at Anyang Maternal and Child Health Hospital from June 2020 to June 2023 were selected as the study subjects.They were divided into a control group and an observation group according to different treatment plans,with 52 cases in each group.The control group received postoperative treatment with pneumatic therapy,while the observation group received additional treatment with low molecular weight heparin on this basis.Both groups maintained treatment for 7 days.Compared two groups of surgical related indicators,incidence of deep vein thrombosis in the lower limbs,coagulation indicators,degree of pain,and quality of life.Result:The observation group had less postoperative bleeding than the control group,shorter hospital stay,and lower incidence of DVT compared to the control group(P<0.05).The coagulation indicators of the observation group were better than those of the control group(P<0.05).There was no significant difference between the two groups of D-dimers(P>0.05).On postoperative days 1,3,5 and 7,the pain scores of the observation group were lower than those of the control group(P<0.05).The quality of life score of the observation group was higher than that of the control group(P<0.05).Conclusion:Low molecular weight heparin combined with pneumatic therapy can effectively reduce the incidence of postoperative DVT in patients undergoing laparoscopic myomectomy,improve coagulation function,and promote faster recovery.