桃红四物汤联合毫火针点刺治疗结节囊肿型痤疮临床疗效观察

Clinical observation on Taohong Siwu Decoction combined with milli fire needle acupuncture in treatment of nodular and cystic acne

目的观察桃红四物汤联合毫火针点刺治疗结节囊肿型痤疮临床疗效及对患者焦虑、抑郁负性情绪的影响。方法将我院120例结节囊肿型痤疮患者随机分为对照组与观察组各60例。对照组给予异维A酸、阿奇霉素联合桃红四物汤治疗,观察组在对照组治疗基础上(仅异维A酸减为2次/d),增加毫火针点刺。比较两组临床疗效,治疗前后的炎性皮损积分、皮肤油脂含量、心理状态及生活质量评分、不良反应发生率及复发率。结果治疗后,观察组总有效率显著高于对照组(P<0.05);两组炎性皮损积分、皮肤油脂含量、心理状态焦虑自评量表(SAS)、抑郁自评量表(SDS)、生活质量(DLQI)评分均低于治疗前(P<0.05),观察组以上指标均低于对照组(P<0.05);观察组不良反应及复发率低于对照组(P<0.05)。结论毫火针点刺疗法联合桃红四物汤治疗结节囊肿型痤疮具有较好的临床效果,可降低炎性皮损程度和皮肤油脂含量,缓解患者焦虑、抑郁情绪,提高生活质量,且不良反应和复发率较低,具有一定的推广应用价值。

Objective To observe the effect of acupuncture with milli fire needle and Taohong Siwu Decoction on cystic acne of phlegm type,and its influence on patients'anxiety and depression.Methods A total of 120 patients with nodular and cystic acne were randomly divided into control group and observation group,with 60 cases in each group.Control group was treated with isotretinoin,azithromycin and Taohong Siwu Decoction,while observation group was treated by acupuncture with milli fire needle based on control group(except for isotretinoin was reduced to 2 times per day),increase milli fire needle prick.The clinical effects of the two groups were compared,and the scores of inflammatory lesions,skin oil content,psychological state and quality of life score,incidence of adverse reactions and recurrence rate before and after treatment was compared.Results After treatment,the total effective rate of observation group was significantly higher than that of control group(P<0.05);the scores of inflammatory skin lesions,skin oil content,psychological state[Self Rating Anxiety Scale(SAS)and Self Rating Depression Scale(SDS)]and quality of life(DLQI)in both groups were significantly lower than those before treatment(P<0.05),and the reduction range of the above indexes in observation group was lower than that in control group(P<0.05);the adverse reaction and recurrence rate in observation group were lower than those in control group(P<0.05).Conclusion It has better clinical effect on adjuvant treatment of cystic acne with phlegm by acupuncture with milli fire needle and Taohong Siwu Decoction,reducing inflammatory skin lesions and skin oil content,relieving anxiety and depression,improving quality of life with higher safety and lower recurrence rate.