临床药师参与1例汉赛巴尔通体脑膜炎的药物治疗分析

Clinical pharmacists participating in the analysis of drug therapy for a case of Bartonella henselae meningitis

临床药师参与1例汉赛巴尔通体脑膜炎患者的抗感染治疗,根据患者临床表现、脑脊液定量宏基因组二代测序(mNGS)检测结果确诊为汉赛巴尔通体感染,参考相关临床指南及国外个案治疗报道,建议选用盐酸米诺环素胶囊口服联合利福平注射液治疗,基于患者脑脊液及相关炎症指标复查结果动态调整患者后续治疗方案。治疗过程中,临床药师发挥专业特长,为患者提供个体化的药学服务,优化抗感染方案,进一步推进临床合理用药。

Clinical pharmacists participated in the anti-infection treatment of a patient with Bartonella henselae meningitis.According to the clinical manifestations and the quantitative metagenomic second-generation sequencing(mNGS)of cerebrospinal fluid,the patient was diagnosed as Bartonella henselae infection.According to the relevant clinical guidelines and foreign case treatment reports,it is recommended to use minocycline hydrochloride capsule oral treatment combined with rifampicin injection.Follow-up treatment of the patient was dynamically adjusted based on the reexamination results of cerebrospinal fluid and related inflammatory indicators.In the treatment process,clinical pharmacists give full play to their professional expertise,provide the patient with individualized pharmaceutical care,optimize anti-infection programs,and further promote clinical rational drug use.