摘要
基于互补金属氧化物半导体(CMOS)有源超材料,通过结合自旋太赫兹源,对生物分子的太赫兹频段指纹谱进行传感检测。对比基于自旋太赫兹源和基于光电导天线的太赫兹时域光谱系统测量的3种不同生物样品的指纹谱特征峰,验证了自旋太赫兹源测量生物样品的可行性。同时,提出一种基于CMOS有源超材料的生物分子太赫兹传感方案,仿真结果表明CMOS调控器件对生物样品的扫描测试表现为生物透射峰与器件谐振峰变化统一。当吸收峰位于器件的调控范围内时,随着加电压的增大,生物透射谱谐振频率减小,出现红移,最大红移量达到40 GHz。因为不同的生物样品有不同的吸收峰,根据不同的太赫兹指纹谱吸收峰的位置设计了5种对应中心频率的CMOS有源超材料,为实现生物分子太赫兹传感系统的小型化和集成化提供了理论及实验基础。
The sensing and detection of the biomolecule Terahertz(THz)spectrum fingerprint is performed based on Complementary Metal Oxide Semiconductor(CMOS)controllable metamaterials,using a Spintronic THz Emitter device.The spintronic THz spectrum fingerprint of three different biological samples were benchmarked with results using THz photoconductive antennas.The results show that the feasibility of measuring biological samples with spin terahertz source is verified.At the same time,a frequency based biomolecular THz sensing scheme is proposed by utilizing CMOS controllable metamaterials.Finite element models are built based on the performance test and the biosensing process of the CMOS controllable metamaterial devices.Five CMOS controllable metamaterials were designed with center frequencies related to the absorption peaks of the biomolecules under test.The simulation results show that the resonance frequency has a red shift with the increase of voltage,and the maximum red shift is up to 40 GHz.This paper provides experimental and theoretical foundations for building miniaturized and integrated biomolecular THz sensing systems.
作者
陈亚玄
孔茹茹
李昭颖
孙统
熊凡
孙芸
刘永山
张有光
白中扬
温良恭
CHEN Yaxuan;KONG Ruru;LI Zhaoying;SUN Tong;XIONG Fan;SUN Yun;LIU Yongshan;ZHANG Youguang;BAI Zhongyang;WEN Lianggong(School of Integrated Circuit Science and Engineering,Beijing 100191,China;School of Electronic Information Engineering,Beijing 100191,China;Shenzhen Innovation Institute,Shenzhen Guangdong 518063,China;Hangzhou Innovation Institute,Beihang University,Hangzhou Zhejiang 310051,China)
出处
《太赫兹科学与电子信息学报》
2024年第2期160-167,共8页
Journal of Terahertz Science and Electronic Information Technology
基金
广东省基础与应用基础研究基金资助项目(2021B1515120012)
青岛市科技惠民示范专项基金资助项目(23-2-8-smjk-3-nsh)。