急性缺氧暴露对人体生理反应及认知能力的影响研究

Effects of Acute Hypoxic Exposure on Human Physiological Response and Cognitive Ability

在低压环境舱开展高海拔环境中人体急性缺氧暴露实验,研究环境压力和温度对人体生理参数和认知能力的影响规律。实验结果表明,随大气压力的降低,人体平均皮肤温度、口腔温度、舒张压、心率和心率变异性均呈增加,而血氧饱和度和收缩压呈降低趋势。其中,平均皮肤温度、心率和血氧饱和度具有显著性差异(p<0.05)。随温度的增加,只有血氧饱和度降低,其他生理参数均升高。其中,平均皮肤温度、心率具有显著性差异(p<0.05)。感知能力、记忆能力和反应能力随大气压力的降低而降低,思辨能力反而提高。其中,记忆能力受压力影响具有显著性(p<0.05)。感知能力和记忆能力随温度的增加有所提高,思辨能力在不同压力下随温度的变化规律不同,反应能力随温度的降低而提高。其中反应能力受温度影响具有显著性(p<0.05)。该研究为保障平原地区人员急进高海拔地区生命健康安全提供有力支撑。

An acute hypoxia exposure experiment was conducted in a low-pressure environment chamber to study the effects of atmospheric pressure and ambient temperature on human physiological parameters and cognitive ability.The experimental results showed that as atmospheric pressure decreased,the average human skin temperature,oral temperature,diastolic blood pressure,heart rate,and heart rate variability increased,while oxygen saturation and systolic blood pressure showed a decreasing trend.Among them,the mean skin temperature,heart rate,and oxygen saturation were significantly different(p<0.05).With the increase in temperature,only oxygen saturation decreased,while all other physiological parameters increased.Among them,the mean skin temperature and heart rate were significantly different(p<0.05).Perception,memory,and reaction abilities decrease with a reduction in atmospheric pressure,while discernment ability increases instead.Among them,memory ability was significantly affected by pressure(p<0.05).Perceptual ability and memory improved as the temperature increased.The discernment ability displayed different patterns of change with temperature under various pressures,whereas the reaction ability increased as the temperature decreased.Among them,reaction ability was significantly affected by temperature(p<0.05).This study provides strong support for safeguarding the life and health safety of personnel in plain areas who ascend to high altitudes.