入伍青年静脉血细胞参数调查研究

Investigation on parameters of venous blood cells in enlisted youth

目的本文从实验室和临床引用参考区间出发,探究《应征公民体格检查办法及标准》中血细胞参考区间是否适宜广大入伍青年人群,初步构建入伍青年血细胞参考区间。方法研究数据来源于2020年7月1日至2022年8月31在甘肃省酒泉市第二人民医院保健科体格检查正常且检测血细胞的入伍青年1507例,依据性别分为入伍男性组(1262例)、女性组(245例),随机抽取健康体检者400例,分为体检男性组(255例)、女性组(145例),比较入伍青年与体检者、《应征公民体格检查办法及标准》和《全国临床检验操作规程》4版、文献资料间的差异,入伍青年以(x±1.96s)建立参考区间;计数入伍青年结果落《全国临床检验操作规程》4版参考区间外比例,并比较入伍青年落参考区间外者间的差异。结果入伍青年中性粒细胞百分比(NEU%)、红细胞数(RBC)、血红蛋白(HB)、红细胞压积(HCT)、红细胞平均血红蛋白浓度(MCHC)检测结果参考区间验证未通过(<90%);入伍青年与健康体检者、《全国临床检验操作规程》4版及参考文献资料比较,结果存在明显差异(P<0.05)。结论入伍男青年部分红细胞参数超《应征公民体格检查办法及标准》和《全国临床检验操作规程》4版参考区间较突出(P<0.05),各实验室应重点关注红细胞系统参数参考区间的适宜性验证及引用,为募集优质兵源和驻区官兵健康保健、临床诊断、治疗提供可靠依据。

Objective This article starts from the reference range of laboratory and clinical reference,To explore whether the reference range of blood cells in the Methods and Standards for Physical Examination of Recruited Citizens is suitable for the vast number of enlisted young people,Preliminary construction of blood cell reference interval for enlisted youth.Methods The research data is from 1507 enlisted youth with normal physical examination and blood cell test in the Health Care Department of the Second People's Hospital of JIUQUAN City,Gansu Province from July 1,2020 to August 31,2022,Divided into enlisted male group according to sex(1262 cases),Female group(145 cases),Randomly select 400 people for physical examination,Divided into physical examination male group(255 cases),Female group(145 ca⁃ses),Compare the differences between the enlisted youth and the physical examiners,the Methods and Standards for Physical Examination of Recruited Citizens and the 4th edition of the National Code of Practice for Clinical Examination,and the literature,All with(x±1.96s).The proportion of the results of enlisted young people outside the reference range of the fourth edition of the National Practice for Clinical Testing,And compare the differences between the enlisted youth who fall outside the REFE.Results The reference interval validation of NEUTOPHIL percentage(NEU%),red blood cell count(RBC),hemoglobin(HB),HEMATOCRIT(HCT)and mean corpuscular hemoglobin concentration(MCHC)test results of young military recruits failed(<90%),The results showed that there were significant differ⁃ences(P<0.05)between the youth enlisted in the army and the health EXAMINEES,the fourth edition of the National Clinical Laboratory Operating Procedures and the references.Conclusion Some red blood cell parameters of enlisted young men exceeded the reference range of the Methods and Standards of Physical Examination for Recruited Citizens and the National Operating Procedures for Clinical Laboratory(Version 4)(P<0.05),The laboratory should focus on the suitability verification and application of reference interval of red blood cell system parameters,To provide reliable basis for health care,clinical diagnosis and treatment of high-quality recruits and soldiers stationed in the region.