仿生超浸润界面传感技术在生物分析中的应用

Application of bioinspired superwettable interface sensing technology in bioanalysis

仿生超浸润界面材料是构建高灵敏度、高特异性生物传感器的一类新兴材料,广泛适用于环境监测、生物医药、食品分析等领域。本文介绍了4种典型的超浸润界面,包括超疏水界面、超亲水界面、超润滑界面以及图案化浸润性界面,总结了界面浸润性调控在电化学、荧光、可视化、表面增强拉曼和可穿戴检测器件等技术中的研究和最新进展,阐述了传感器构建机理和检测机制。最后,对仿生超浸润界面传感技术在生命分析应用中存在的问题和现存的挑战进行了总结和讨论。

Bioinspired superwettable materials are a type of emerging materials to construct high-sensitivity and high-specificity biosensors, which are widely applicable in fields of environmental monitoring, biomedicine, and food analysis. This review introduces four typical superwettable interfaces, including superhydrophobic interfaces, superhydrophilic interfaces, slippery interfaces, and patterned superwettable interfaces. It summarizes the research and latest advances of superwettability regulation in technologies such as electrochemistry, fluorescence, visualization, surface-enhanced Raman spectroscopy, and wearable detection devices, and elucidates the construction mechanisms and detection mechanisms of sensors. Finally, the problems and existing challenges of bioinspired superwettable sensing technology in biological analysis applications are summarized and discussed.