针刺蝶腭神经节治疗变应性鼻炎疗效的Meta分析

A Meta-analysis of the Therapeutic Effects of Acupuncture Sphenopalatine Ganglion on Allergic Rhinitis

目的 系统评价针刺蝶腭神经节治疗变应性鼻炎的临床疗效。方法 计算机检索中国知网(China National Knowledge Internet,CNKI)、万方、维普(VIP China Science and Technology Journal Database,VIP)、中国生物医学(Chinese Bio Medical Literature Database,CBM)、PubMed、Web of Science、Cochrane Library数据库,针刺蝶腭神经节治疗变应性鼻炎的随机对照文献,剔除低质量文献,运用Rev Man5.4软件进行Meta分析。结果 9篇RCT共733例患者;Meta分析提示针刺蝶腭神经节可以改善患者生活质量(P=0.04,MD=5.62,95%CI=[0.24,10.99])、减轻变应性鼻炎四大主症(P=0.02,MD=1.24,95%CI=[0.23,2.25])、对变应性鼻炎的治疗总有效率优于常规治疗(P=0.002,RR=1.15,95%CI=[1.05,1.26]),尤其优于常规针刺。结论 针刺蝶腭神经节治疗变应性鼻炎简便易行,疗效确切,可显著改善患者症状,提高生活质量,建议临床推广应用。

Objective To systematically evaluate the clinical efficacy of acupuncture of the pterygopalatine ganglion in the treatment of allergic rhinitis.Methods Computer search of randomized controlled literature on allergic rhinitis treated by acupuncture of the pterygopalatine ganglion,excluding low-quality literature,using the Rev Man 5.4 software for Meta-analysis,was conducted in China National Knowledge Internet(CNKI),Wan Fang,VIP China Science and Technology Journal Database(VIP),Chinese Bio Medical Literature Database(CBM),PubMed,Web of Science and Cochrane Library.Results A total of 733 patients in 9 RCTs were collected.Meta-analysis suggested that acupuncture of the pterygopalatine ganglion improved patients' quality of life(P=0.04,MD=5.62,95% CI=[0.24,10.99]),and reduced the four main symptoms of allergic rhinitis(P=0.02,MD=1.24,95% CI= [0.23,2.25]).The total therapeutic efficiency was better than conventional treatment(P=0.002,RR=1.15,95% CI= [1.05,1.26]),and especially better than conventional acupuncture.Conclusion The treatment of allergic rhinitis by acupuncture of the pterygopalatine ganglion is simple and easy,with definite efficacy,which can significantly improve patients' symptoms and quality of life,and is recommended for clinical application.