司美格鲁肽治疗2型糖尿病合并动脉粥样硬化性心血管疾病、肝肾功能不全1例

Semaglutide in the Treatment of Type 2 Diabetes Mellitus Complicated with Atherosclerotic Cardiovascular Disease and Liver and Kidney Insufficiency:A Case Report

男性患者1例,66岁,因“反复胸痛3年,加重8.5 h”入住瑞金市人民医院,明确诊断为2型糖尿病合并动脉粥样硬化性心血管疾病(ASCVD);冠脉造影诊断:冠状动脉粥样硬化性心脏病,冠状动脉慢血流。予餐时+基础胰岛素的强化降糖治疗方案,患者血糖控制不佳;考虑患者合并ASCVD、肝肾功能不全,联合长效胰高糖素样肽-1受体激动剂司美格鲁肽治疗,血糖控制满意。

The patient was a 66-year-old male,who was admitted to People's Hospital of Ruijin due to"repeated chest pain for 3 years,aggravated for 8.5 hours",and was definitely diagnosed as type 2 diabetes with atherosclerotic cardiovascular disease(ASCVD);coronary angiography diagnosis:coronary artery slow flow of coronary atherosclerotic heart disease.The intensified hypoglycemic treatment plan with meal time and basal insulin was administered,but the patient's blood sugar control was poor.Considering the patient's comorbidities with ASCVD and liver and kidney dysfunction,the combination of long-acting glucagon like peptide-1 receptor agonist smeglutide was used for treatment,and the blood sugar control was satisfactory.