方剂组学高质量发展要义

Essentials for high-quality development of fangjiomics

现代组学技术的发展,如组学相关技术的引进促进了方剂作用原理的研究,创新发展了一些新的方剂复杂药理分析技术,但总体而论以前的思路仅仅在应用层面,未能与方剂的学科内涵结合起来,更不能在方剂学科未来发展及指导临床有效性与安全性深入研究方面发挥应有的作用,不忘本来,兼容外来,面向未来,因此该文提出“整体、宏观、实践”三要义以探索方剂组学高质量发展的未来发展方向。

The development of modern omics technology has facilitated in-depth research on many disciplines in the field of medicine.For instance,the introduction of omics-related technology has facilitated research on the mechanism of formula′s action and led to the innovative development of sophisticated pharmacological analysis methods.However,in general,the previous ideas are only limited to the application level,failing to integrate with the discipline connotation of formulaology.Furthermore,they are unable to fulfill their potential role in the future evolution of formulaology and steer comprehensive research on the clinical efficacy and safety of formulas.We should not forget our origins,which are compatible with other countries,and embrace the future.Therefore,this paper proposes the three essentials of"holism,macro,and practice"to investigate the future direction of high-quality development in fangjiomics.