纤维乳管镜联合超声乳管造影对病理性乳头溢液的诊断价值研究

The diagnostic value study of fiberoptic ductoscopy combined with ultrasound galactography in pathological nipple dis⁃charge

目的 探讨纤维乳管镜(fiberoptic ductoscopy, FDS)联合超声乳管造影对病理性乳头溢液(pathological nipple discharge, PND)的诊断价值。方法 选取山东省立第三医院就诊并行手术治疗的40例PND患者,结合病理结果分析X线乳管造影、FDS及FDS联合超声乳管造影对PND诊断的准确率、灵敏度、特异度、阳性及阴性预测值。结果 40例患者术后病理证实恶性病变9例,良性病变31例。FDS联合超声乳管造影诊断结果和病理诊断结果一致性较强。FDS联合超声乳管造影诊断PND的准确率、灵敏度、特异度、阳性预测值和阴性预测值均高于X线乳管造影和FDS单独诊断。结论 FDS联合超声乳管造影对PND具有较高的诊断价值,能提高早期诊断率,避免漏诊或盲目的手术干预。

Objective To evaluate the diagnostic value of fiberoptic ductoscopy(FDS)combined with ultrasound galactography in pathological nipple discharge(PND).Methods A total of 40 patients with PND who underwent surgical treatment in the Shandong Provincial Third Hospital were collected.Combined with pathological results,the accuracy,sensitivity,specificity,positive and negative predictive values of X-ray galactography,FDS and FDS combined with ultrasound galactography in the diagnosis of PND were analyzed.Results The postoperative pathology results of 40 patients confirmed malignancy in 9 cases and benignity in 31 cases.The consistency between the diagnostic results of FDS combined with ultrasound galactography and the pathologic diagnostic results was strong.The accuracy,sensitivity,specificity,positive predictive value and negative predictive value of PND diagnosed by FDS combined with ultrasound galactography were higher than that of X-ray galactography or FDS alone.Conclusion FDS combined with ultrasound galactography has a high diagnostic value for PND,which improves the early diagnostic rate and avoids the missed diagnosis or blind surgical intervention.