摘要
脉动流实验不仅能在临床前对各种人工心脏瓣膜(prosthetic heart valve,PHV)的临床安全性和有效性进行评估,而且在最新的计算模型和流体仿真实验中起重要作用,能够为PHV的性能优化提供实验依据,被认为是评价PHV流体力学性能的金标准。本文主要回顾脉动流实验的发展历史,阐述常用脉动流模拟装置的特点,并讨论脉动流实验未来的发展方向。目前国外在脉动流模拟装置的研发方面处于领先地位,国内在此领域有很大的发展空间,期望能得到进一步的关注和研究。
The pulsatile flow experiment can not only evaluate the preclinical safety and risk of prosthetic heart valve(PHV)but also play an important role in the computational model and fluid simulation,providing an experimental basis for the performance optimization of PHV.This paper mainly reviews the development and the latest progress of PHV pulsatile flow experiments and the characteristics of experimental pulse duplicator,and discuss the research direction of pulsatile flow experiments,expecting a further development in this field.
作者
祁亮
张民祖
宋兵
强彦
QI Liang;ZHANG Minzu;SONG Bing;QIANG Yan(The First School of Clinical Medicine,Lanzhou University,Lanzhou,730000,P.R.China;Department of Cardiovascular Surgery,The First Hospital of Lanzhou University,Lanzhou,730000,P.R.China;School of Energy and Power Engineering,Lanzhou University of Technology,Lanzhou,730050,P.R.China)
出处
《中国胸心血管外科临床杂志》
CSCD
北大核心
2024年第3期473-477,共5页
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
基金
国家自然科学基金项目(51966010)
甘肃省自然科学基金项目(21JR11RA090)。
关键词
人工心脏瓣膜
脉动流实验
脉动流模拟装置
流体动力学
综述
Prosthetic heart valve
pulsatile flow experiment
experimental pulse duplicator
fluid dynamics
review
