摘要
局部晚期头颈部鳞状细胞癌(head and neck squamous cell carcinoma,HNSCC)是临床治疗的难点,传统的治疗方式包含手术、放疗和化疗在内的多模式治疗,但治疗疗效有限。近期开展的临床研究将免疫检查点抑制剂应用于局部晚期HNSCC的新辅助治疗中,以期提高治疗疗效并增加挽救手术的有效性。但目前新辅助免疫治疗的疗效尚不明确,临床试验仍在不断探索。本文旨在综述新辅助免疫治疗在局部晚期HNSCC患者中的研究进展,对局部晚期HNSCC患者的治疗提供参考。
作者
宋艺璇
桂琳
刘绍严
Song Yixuan;Gui Lin;Liu Shaoyan(Department of Head and Neck Surgical Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100021,China;Department of Medical Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs,Beijing 100021,China)
出处
《中华耳鼻咽喉头颈外科杂志》
CSCD
北大核心
2024年第2期187-191,共5页
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
