取卵术中不同负压吸引压力值对妊娠结局的影响

Influence of Different Suction Pressure Values During Oocyte Retrieval on Pregnancy Outcome

目的:探讨取卵术中不同负压吸引压力值对妊娠结局的影响。方法:选取2019年2月—2020年2月江西省妇幼保健院生殖中心收治的107例行辅助生殖技术的不孕症患者作为研究对象,使用随机摸球法将其分为A组(n=35)、B组(n=36)和C组(n=36),三组患者分别设置100 mmHg (1 mmHg=0.133 kPa)、130 mmHg、160 mmHg负压吸引压力。比较三组患者的获卵率、优质胚胎率、受精率、生化妊娠率、临床妊娠率、进针次数、穿刺持续时间、穿刺过程中出血量。结果:B组患者进针次数、穿刺持续时间分别为(2.61±0.54)次、(9.87±2.14) min,C组患者进针次数、穿刺持续时间分别为(2.47±0.39)次、(9.76±2.32) min,均低于A组的(3.41±0.87)次、(13.21±3.74) min,C组患者取卵过程中的出血量为(1.51±0.61) mL,高于A组、B组的(0.64±0.12) mL、(0.63±0.21) mL,差异有统计学意义(P<0.05),B组患者的优质胚胎率(75.00%)明显高于A组(51.43%),差异有统计学意义(P<0.05)。结论:取卵术中设置130 mmHg的负压能够提高优质胚胎率,设置较小的压力能够获得更高的操作安全性,但临床实际过程中需根据具体情况进行压力选择,以获得更佳的妊娠结局。

Objective:To explore the influence of different suction pressure values on pregnancy outcome during egg retrieval.Methods:107 infertility patients with assisted reproductive technology who were admitted to the reproductive center of the hospital from February 2019 to February 2020 were selected as the research objects.They were divided into group A(n=35),group B(n=36)and group C(n=36) with random touch ball method.Three groups were respectively set with different negative pressure suction pump pressures.Group A was 100 mmHg(1 mmHg=0.133 kPa),group B was 130mmHg,and group C was 160mmHg.The egg retrieval rate,high-quality embryo rate,fertilization rate,biochemical pregnancy rate,clinical pregnancy rate,number of needles,duration of puncture,and blood loss during puncture were compared among three groups.Results:The number of needle injections and puncture duration in Group B patients were(2.61±0.54) times and(9.87±2.14) minutes,respectively.The number of needle injections and puncture duration in group C patients were(2.47±0.39) times and(9.76±2.32) minutes,respectively,which were lower than those in group A(3.41±0.87) times and(13.21±3.74) minutes.The amount of bleeding during egg retrieval in Group C patients was(1.51±0.61) ml,which was higher than those in Group A and Group B(0.64±0.12) ml and(0.63±0.21) ml(P<0.05).The high-quality embryo rate of group B patients(75.00%) was significantly higher than that of group A(51.43%)(P<0.05).Conclusion:Setting a negative pressure of 130 mmHg during oocyte retrieval can increase the rate of high-quality embryos.Setting a smaller pressure can achieve higher operational safety.However,in clinical practice,pressure selection needs to be based on specific circumstances to achieve better pregnancy outcomes.