二联药物方案对BPPV管石复位后残余眩晕患者临床症状及负面情绪的影响

Dichotomous Drug Regimen in Patients with Residual Vertigo after BPPV Canalith Repositioning:Clinical Symptoms and the Impact of Negative Emotions

目的探讨联合药物方案对良性阵发性位置性眩晕(BPPV)管石复位后残余眩晕患者临床症状及负面情绪的影响。方法回顾性分析我院收治的BPPV管石复位后残余眩晕患者共78例临床资料,其中单纯采用倍他司汀治疗43例设为对照组,在倍他司汀基础上联用利多卡因治疗35例设为观察组;比较两组眩晕症状消失时间、治疗前后DHI量表评分、SAS量表评分、SDS量表评分及随访复发情况。结果观察组眩晕症状消失时间显著少于对照组(P<0.05);观察组患者治疗后1周、2周及3周DHI量表评分均显著低于对照组、治疗前(P<0.05);观察组患者治疗后3周SAS和SDS量表评分均显著低于对照组、治疗前(P<0.05);两组患者均随访3个月,未见复发病例。结论联合药物方案治疗BPPV管石复位后残余眩晕可有效缩短起效时间,提高眩晕症状控制效果,并有助于缓解负面情绪。

Objective Investigate the impact of a combined medication regimen on the clinical symptoms and negative emotions of patients with residual dizziness after canalith repositioning for Benign Paroxysmal Positional Vertigo(BPPV).Methods A retrospective analysis was conducted on clinical data from 78 patients with residual dizziness after canalith repositioning for BPPV treated at our hospital.Among them,43 patients treated solely with betahistine were assigned to the control group,and 35 patients treated with a combination of betahistine and lidocaine were assigned to the observation group.The study compared the time for dizziness symptoms to disappear,Dizziness Handicap Inventory(DHI)scores before and after treatment,as well as SAS and SDS scale scores,and follow-up recurrence situations between the two groups.Results The disappearance time of dizziness symptoms in the observation group was significantly shorter than in the control group(P<0.05).The DHI scores of the observation group were significantly lower than those of the control group and pre-treatment at 1,2 and 3 weeks post-treatment(P<0.05).Additionally,SAS and SDS scale scores of the observation group were significantly lower than those of the control group and pre-treatment at 3 weeks post-treatment(P<0.05).Both groups were followed up for 3 months,and no recurrence was observed.Conclusion A combined drug regimen for treating residual dizziness after BPPV canalith repositioning is effective in reducing the onset time,enhancing the control of dizziness symptoms,and aiding in alleviating negative emotions.