期刊文献+

改良仲景黄土汤联合艾司奥美拉唑钠治疗肝硬化上消化道出血的临床疗效

下载PDF
导出
摘要 目的:探讨改良仲景黄土汤联合注射用艾司奥美拉唑钠对肝硬化上消化道出血患者的临床效果。方法:择取2019年6月至2022年5月广东省人民医院赣州医院收治的肝硬化上消化道出血患者66例,随机分为两组,各33例。对照组患者行注射用艾司奥美拉唑钠治疗,观察组患者在对照组的基础上施以改良仲景黄土汤治疗,记录两组患者症状改善效果,统计止血情况,评估胃肠功能,分析安全性。结果:观察组患者治疗后吐血缠绵、神疲乏力、面色少华及舌淡苔白积分均低于对照组;观察组患者的止血时间短于对照组;观察组患者治疗后血清纤维蛋白原(FIB)高于对照组,血清D–二聚体(D–D)低于对照组;观察组患者治疗后血清胃动素(MTL)、胃泌素(GAS)均低于对照组,上述差异均具有统计学意义(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论:改良仲景黄土汤联合注射用艾司奥美拉唑钠用于肝硬化上消化道出血患者治疗,症状获有较佳改善,止血良好,胃肠功能得到增强,且不良反应较少。
出处 《深圳中西医结合杂志》 2023年第24期66-68,共3页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
  • 相关文献

参考文献3

二级参考文献23

  • 1周宜,陈钢,夏丽娜,徐薇.从《内经》“有故无殒”思想看中药毒性研究[J].中国中医基础医学杂志,2007,13(5):342-343. 被引量:34
  • 2Sheng X Y, Wang M, Lu M, et al. Rhein ameliorates fatty liver disease through negative energy balance, hepatic lipogenic regulation, and immunomodulation in diet-induced obese mice[J]. Am J Physiol Endocrinol Metab,2011,300:E886.
  • 3Zhao Y L, Wang J B, Zhou G D, et al. Investigations of free anthraquinones from rhubarb against α-naphthylisothiocyanate-induced cholestatic liver injury in rats[J]. Basic Clin Pharmacol Toxicol, 2009,104:463.
  • 4Nasr S H, D\'Agati V D, Said S M, et al. Oxalate nephropathy complicating Roux-en-Y gastric bypass: an underrecognized cause of irreversible renal failure[J]. Clin J Am Soc Nephrol, 2008,3:1676.
  • 5Yan M, Zhang L-Y, Sun L-X, et al. Nephrotoxicity study of total rhubarb anthraquinones on Sprague Dawley rats using DNA microarrays[J]. J Ethnopharmacol,2006,107:308.
  • 6Xiang Y Z, Shang H C, Gao X M, et al. A comparison of the ancient use of ginseng in traditional Chinese medicine with modern pharmacological experiments and clinical trials[J]. Phytother Res,2008,22(7):851.
  • 7Wang J-b, Zhao H-p, Zhao Y-l, et al. Hepatotoxicity or hepatoprotection pattern recognition for the paradoxical effect of the Chinese herb Rheum palmatum L. in treating rat liver injury[J]. PLoS ONE,2011,6(9):e24498.
  • 8Napoli J, Prentice D, Niinami C, et al. Sequential increases in the intrahepatic expression of epidermal growth factor, basic fibroblast growth factor, and transforming growth factor beta in a bile duct ligated rat model of cirrhosis[J]. Hepatology, 1997,26(3):624.
  • 9Miele L, Forgione A, La Torre G, et al. Serum levels of hyaluronic acid and tissue metalloproteinase inhibitor-1 combined with age predict the presence of nonalcoholic steatohepatitis in a pilot cohort of subjects with nonalcoholic fatty liver disease[J]. Transl Res,2009,154(4):194.
  • 10Bourbonnais E, Raymond V A, éthier C, et al. Liver fibrosis protects mice from acute hepatocellular injury[J]. Gastroenterology,2012,142:130.

共引文献173

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部