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The Warburg effect drives dedifferentiation through epigenetic reprogramming

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摘要 German biochemist and cell physiologist,Otto H.Warburg(Figure 1),made a groundbreaking discovery in 1923.Specifically,tumors were shown to consume large amounts of glucose and ferment glucose into lactate,even in the presence of oxygen—a phenomenon termed"aerobic glycolysis"1,2.This phenomenon,later named the Warburg effect by Efraim Racker in the 1970s,remains pivotal in cancer research3.
出处 《Cancer Biology & Medicine》 SCIE CAS CSCD 2023年第12期891-897,共7页 癌症生物学与医学(英文版)
基金 supported by a Stanford Maternal and Child Health Research Institute Research Scholar Award (2020) an American Cancer Society Research Scholar Grant (RSG-20-036-01) an Agilent Solutions Innovation Research Award (SIRA) to J.Y.
关键词 WARBURG EFFECT FIGURE
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