经方洗胃治疗结直肠癌术后胃瘫临床观察

Classical Prescription Gastric Lavage in the Treatment of Postoperative Gastroparesis of Colorectal Cancer

目的探讨经方洗胃治疗结直肠癌术后胃瘫的效果及对兴奋性递质神经降压素(NT)的影响。方法选取九江市中医院肛肠科收治的结直肠癌术后胃瘫患者60例,按随机数字表法分成治疗组(枳实消痞丸洗胃)和对照组(枸橼酸莫沙必利片口服),各30例;连续治疗4周,观察治疗效果。结果治疗前,两组各项指标均无统计学意义(P>0.05);治疗后,治疗组胃瘫缓解率更高、胃瘫症状积分更低,胃液引流量、胃管留置时间改善更好,血清NT含量更低(P<0.05)。治疗组总有效率为100.00%(30/30),优于对照组的93.33%(28/30)(P<0.01)。结论经方活用洗胃干预结肠癌术后胃瘫患者,能显著改善其临床症状,提高临床疗效,降低兴奋性递质NT含量。

Objective To investigate the effect of classical prescription gastric lavage on postoperative gastroparesis and observe the effect of excitatory transmitter NT.Methods A total of 60 patients with postoperative gastroparesis of colorectal cancer admitted to Jiujiang Hospital of Traditional Chinese Medicine were selected as the study subjects,and were randomly divided into treatment group(Zhishi Xiaopi pill gastric lavage)and control group(Mosapride tablets orally),with 30 patients in each group.The treatment continued for four weeks.The treatment effect was observed,recorded and analyzed.Results Before treatment,there was no statistical significance in all indexes in 2 groups(P>0.05).After treatment,the remission rate of gastroparesis was higher,the score of gastroparesis symptoms was lower,the gastric drainage flow,the retention time of gastric tube were better improved,and the serum NT content was lower(P<0.05).The total effective rate of the treatment group was 100.00%(30/30),which was better than that of control group(93.33%,28/30)(P<0.01).Conclusion Classical prescription gastric lavage can significantly improve clinical symptoms,improve clinical efficacy and reduce the content of excitatory transmitter NT in patients with gastric paralysis after colorectal cancer operation.