八段锦改善围绝经期综合征伴抑郁症状的Meta分析

Meta Analysis of Baduanjin in Improving Perimenopausal Syndrome with Depression

目的评价八段锦改善围绝经期综合征伴抑郁症状的疗效。方法检索中英文数据库中关于八段锦改善围绝经期综合征伴抑郁症状疗效的随机对照试验(RCT),使用Revman 5.4.1进行Meta分析。结果纳入文献5篇,方法学质量中等偏上。Meta分析显示:试验组抑郁自评量表(SDS)及流行病学研究中心抑郁量表(CES-D)评分均低于对照组,差异均有统计学意义(P<0.001);试验组Kupperman评分低于对照组,差异有统计学意义(P<0.001),为排除其高异质性原因,剔除一项研究后,差异仍有统计学意义(P<0.001)。纳入文献均未提到不良反应。结论八段锦对改善围绝经期综合征伴抑郁症状起到积极作用,但仍需更多高质量研究支持该结论。

Objective To evaluate the curative effect of Baduanjin on perimenopausal syndrome with depression.Methods Randomized controlled trials of Baduanjin in improving the curative effect of perimenopausal syndrome with depression were searched in Chinese and English databases,and meta-analysis was conducted by Revman5.4.1.Results Five literatures were included,and the methodological quality was above average.Meta-analysis showed that the scores of SDS and CES-D in the experimental group were lower than those in the control group,and the differences were statistically significant(P<0.001).The Kupperman score of the experimental group was lower than that of the control group,and the difference was statistically significant(P<0.001).In order to eliminate the reasons for its high heterogeneity,the difference was still statistically significant after one study was excluded(P<0.001).No adverse reactions were mentioned in the included literature.Conclusion Baduanjin plays a positive role in improving the symptoms of perimenopausal syndrome with depression,but more high-quality studies are needed to support this conclusion.