摘要
对国内外文献报道的端粒长度与疾病发生风险的孟德尔随机化研究现状进行了综述,并分析孟德尔随机化研究的优势和局限性,为进一步了解端粒长度对人类疾病的治疗及预防提供新的方向。
The article reviewed the current status of Mendelian randomization research on telomere length and disease risk reported in domestic and foreign literature,and analyzed the advantages and limitations of Mendelian randomization research,providing a new direction for further understanding the treatment and prevention of telomere length in human diseases.
作者
曹素娴
钟廉
吴培炜
刘爽
王海东
周小燕
CAO Suxian;ZHONG Lian;WU Peiwei;LIU Shuang;WANG Haidong;ZHOU Xiaoyan(Medical School of Yan'an University,Yan'an 716000,CHN;School of Pharmaceutical Science,Guangzhou University of Chinese Medicine,Guangzhou 510006,CHN)
出处
《河南大学学报（医学版）》
CAS
2024年第1期6-11,共6页
Journal of Henan University:Medical Science
关键词
端粒长度
疾病风险
孟德尔随机化
telomere length
disease risk
Mendelian randomization
