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细胞因子与青光眼滤过手术后滤过通道瘢痕化的相关性研究

CORRELATION BETWEEN CYTOKINES AND SCARRING OF FILTRATION CHANNELS AFTER GLAUCOMA FILTRATION SURGERY
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摘要 青光眼已成为全球首位不可逆致盲疾病,眼压是预防视力丧失唯一可控因素。约20%的患者在药物治疗下眼压控制效果不佳,需行滤过手术,但术后滤过通道瘢痕化会导致眼压再度升高。房水与滤过通道瘢痕化的机制紧密相关,房水中各种细胞因子含量的变化为我们了解青光眼滤过术后滤过通道瘢痕化提供了重要线索。故本文针对细胞因子与滤过手术预后的相关性进行综述和回顾。 Glaucoma has become the world's first irreversible blinding disease,and intraocular pressure is the only controllable factor in preventing vision loss.About 20%of patients do not control IOP well with medical therapy and require filtration surgery,but postoperative scarring of the filtration channel can lead to a re-increase in intraocular pressure.Aque-ous humor is closely related to the mechanism of scarring of the filtration channel,and the changes in the content of various cytokines in aqueous humor provide important clues for us to understand scarring after glaucoma filtration.Therefore,this ar-ticle reviews and reviews the correlation between cytokines and the prognosis of filtration surgery.
作者 牛越 刘嘉方 陈启 史桂桃 NIU Yue;LIU Jiafang;CHEN Qi;SHI Guitao(College of Graduate,Inner Mongolia Medical University,Hohhot 010059,China;Ningxia Medical University,Yinchuan 750004,China;Department of Ophthalmology,The Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010050,China)
出处 《内蒙古医科大学学报》 2023年第6期647-650,共4页 Journal of Inner Mongolia Medical University
基金 内蒙古自治区自然科学基金项目(2020LH08020)。
关键词 细胞因子 滤过手术 成纤维细胞 瘢痕化 青光眼 Cytokine Filtration surgery Scarring Fibroblast Glaucoma
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