脉络膜生理特性及其与儿童青少年近视的关联

Physiological characteristics of the choroid and its association with myopia in children and adolescents

脉络膜是位于巩膜和Bruch膜之间的一个多功能动态结构,可能参与了眼球生长调节与近视发展,脉络膜厚度可能是预测儿童青少年近视发展及治疗防控效果的重要生物标志物。研究对脉络膜的生理结构、测量方法进行了综述和总结,探讨了脉络膜的影响因素,包括年龄、生理变化、屈光状态和眼轴长度、药物影响及光学环境等,指出了脉络膜厚度在儿童青少年近视研究中可能的应用。

The choroid is a multifunctional dynamic structure located between the sclera and the Bruch membrane,which may be involved in the regulation of eye growth and the development of myopia.Choroidal thickness may serve as an important biomarker for predicting the development of myopia and the effectiveness of myopia control treatments in children and adolescents.The study reviews and summarizes the physiological structure and measuring methods of the choroid,and discusses its influencing factors including age,physiological changes,refractive status,axial length,drug effects,optical environment and so on.The review points out the potential applications of choroidal thickness in myopia research among children and adolescents.