心脏自主神经消融治疗缓慢性心律失常研究进展

Research progress in cardiac autonomic nerve ablation in the treatment of bradycardia

缓慢性心律失常是各种原因引起的长RR间期,其中部分由心血管反射因素触发而引起功能性心动过缓或传导延缓、中断,严重者可引起晕厥,后者又称之为心脏抑制型血管迷走性晕厥(VVS)。心脏自主神经节(GP)消融在近二十年中发展迅速,并已被证明是治疗VVS及相关心动过缓的有效方法。影响GP消融成功率的因素包括:具体的消融部位、GP定位、手术技术、消融终点评估以及其他干预措施的整合。文章就GP消融治疗VVS及心动过缓的最新进展做一综述。

Bradycardiac arrhythmias are characterized by prolonged RR intervals resulting from various etiologies,and in some cases cardiovascular reflex inducements trigger functional bradycardia or delayed or interrupted conduction.Severe cases may present syncope,also known as cardiac inhibitory vasovagal syncope(VVS).Over the past two decades,rapid advancements in ganglionated plexi(GP)ablation have demonstrated its efficacy in treating VVS and associated bradycardia.Factors influencing the success rate of GP ablation include specific ablation site,GP localization,surgical technique,assessment of ablation endpoint,and integration of other interventions.This article reviews the latest advancements in GP ablation treatment for VVS and bradycardia.