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肿瘤免疫治疗的机遇与挑战

Opportunities and challenges in tumor immunotherapy
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摘要 随着免疫检查点抑制剂的发现和成功应用,肿瘤免疫治疗成为肿瘤临床治疗的又一有效手段。本文从细胞免疫治疗、免疫检查点抑制剂和双特异性抗体3个方面对肿瘤免疫治疗的现状及存在的问题和挑战进行综述。 With the development and successful application of immune checkpoint inhibitors,tumor immunotherapy has returned to another effective means in the clinical treatment of tumor.Here,we briefly reviews the current status of cumor im⁃munotherapy three aspects:cell therapy,immune checkpoint inbhitors,and bispecific antibodies,and disscussed the existing problems and challenges.
作者 陈奕 丁健 CHEN Yi;DING Jian(State Key Laboratory of Chemical Biology,Shanghai Institute of Materia Medica Chinese Academy Sciences,Shanghai 201203,China;Shandong Laboratory of Yantai Drug Discovery,Shandong Yantai 264117,China;Bohai Rim Advanced Research Institute for Drug Discovery,Shandong Yantai 264117,China;State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica Chinese Academy Sciences,Shanghai 201203,China)
出处 《临床药物治疗杂志》 2024年第1期1-6,25,共7页 Clinical Medication Journal
关键词 肿瘤免疫治疗 细胞免疫治疗 免疫检查点疗法 双特异性抗体 tumor immunotherapy immune cell therapy immune checkpoint therapy bispecific antibodies
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