西藏地区高血压幕上脑出血运用多田公式测算血肿体积的准确性和可靠性研究

Study on the Accuracy and Reliability of the Measurement of Hematoma Volume by Using the Coniglobus Formula for Hypertensive Supratentorial Cerebral Hemorrhage in Xizang

目的 以3D-Slicer软件针对西藏地区高血压幕上脑出血血肿量测量结果比较,研究多田公式计算血肿体积的准确性和可靠性。方法 收集2021年1月至2022年12月收治的146例高血压性幕上出血患者的入院颅脑CT平扫影像学资料,分别采用多田公式和3D-Slicer软件测量血肿体积。将血肿体积分为:<30mL(n=58),30mL(n=88);按形状分组:规则组(n=59)、不规则组(n=87)。根据血肿大小和形状运用两种方法对血肿体积测量结果进行分析。结果 146名脑出血患者分别用3D-Slicer及多田公式进行血肿量计算,数据表明采用3DSlicer计算的血肿量(41.83±22.79)mL高于采用多田公式计算的血肿量(35.65±17.87)mL,此差异是统计学显著的,t(145)=13.078,p<0.001;血肿<30mL数据表明采用3D-Slicer计算的血肿量(18.76±6.67)mL高于采用多田公式计算的血肿量(17.86±5.68)mL具有显著统计学差异;血肿30mL组用3D-Slicer计算的血肿量(57.04±15.74)mL高于采用多田公式计算的血肿量(47.38±12.69)具有显著统计学差异。形态规则组数据表明采用3DSlicer计算的血肿量(34.29±21.90)mL高于采用多田公式计算的血肿量(30.37±17.36)mL具有显著统计学差异;形态不规则组数据表明采用3D-Slicer计算的血肿量(46.95±22.06)mL高于采用多田公式计算的血肿量(39.23±17.42)mL具有显著统计学差异。结论 多田公式针对高血压脑出血幕上较大量血肿、形态不规则血肿测算结果误差较大、准确性差。

Objective This study aims to assess the accuracy and reliability of the coniglobus formula for calculating the volume of hematoma by comparing the measurement resluts of hypertensive supratentorial cerebral hemorrhage hematoma by 3D-Slicer software in Xizang.Methods The non-contrast CT imaging data of 146 patients with hypertensive supratentorial hemorrhage admitted from January 2021 to December 2022 were collected,and the hematoma volumes was measured by the Coniglobus Formula and 3D-Slicer software,respectively.The hematoma volume was divided into<30 mL(n=58)and 30 mL(n=88),and it grouped by shape was regular(n=59)and irregular(n=87).The hematoma volume meaurements were analyzed by using two methods depending on the size and shape of the hematoma.Results The data showed that the hematoma volume calculated by 3D-Slicer(41.83±22.79 mL)was higher than that caculated by the Coniglobus Formula(35.65±17.87 mL),and the difference was significant,t(145)=13.078,p<0.001.The data of hematoma<30mL revealed that the hematoma volume calculated by 3D-Slicer(18.76±6.67 mL)was higher than that calculated by the Coniglobus Formula(17.86±5.68 mL),which was a significant statistical difference.The hematoma volume calculated by the 3D-Slicer(57.04±15.74 mL)in the hematoma 30mL group was higher than that calculated by the Coniglobus Formula(47.38±12.69 mL),which had significant statistical difference.The regular morphology group showed that the hematoma volume calculated by 3D-Slicer(34.29±21.90mL)was higher than that calculated by Coniglobus formula(30.37±17.36mL),which was a significant statistical difference.Meanwhile,the data of the irregular morphology group showed that the hematoma volume calculated by 3D-Slicer(46.95±22.06mL)was higher than that calculated by Coniglobus formula(39.23±17.42mL),and there was a significant statistical difference.Conclusion In terms of the large amount of supratentorial hematoma and irregular hematoma of hypertensive intracerebral hemorrhage,the calculation results of the Coniglobus Formula have great error and poor accuracy.