血栓弹力图在脑卒中的应用进展

Advances in the application of thromboelastography in stroke

脑卒中是人类健康生存中的一个重要挑战,其具有高致残率、高致死率和高复发率的特点,给家庭和社会带来巨大的负担,影响社会发展。因脑卒中发展迅速,对其疾病的监测及治疗成为医学研究中的一项重要内容。血栓弹力图(TEG)是一种快速型凝血检测方法,作为较新发展的凝血功能检测平台,能够全面反映凝血因子活性、血小板和纤维蛋白原功能等凝血相关因素的异常,便于临床医生进行疾病监测、治疗评估和预后预测。现本文通过对TEG基本概念、主要参数及临床意义在脑卒中诊疗及预后中的应用进行综述。

Stroke is an important challenge for the healthy survival of humans and is characterized by high disability,mortality,and recurrence rates,which brings huge burden to family and society and affects social development.Due to the rapid progression of stroke,the monitoring and treatment of this disease has become an important part of medical research.Thromboelastography(TEG)is a rapid coagulation detection method,and as a newly developed platform for coagulation function detection,it can fully reflect abnormalities in the activity of coagulation factors and the coagulationrelated factors such as platelet and fibrinogen function,which is convenient for clinicians to conduct disease monitoring,treatment evaluation,and prognosis prediction.This article reviews the basic concepts,main parameters,and clinical significance of TEG and its application in the diagnosis,treatment,and prognosis of stroke.