探讨介入栓塞术在脑动脉瘤临床治疗中的应用价值

Exploring the Application Value of Interventional Embolization in the Clinical Treatment of Cerebral Aneurysm

目的探讨介入栓塞术在脑动脉瘤临床治疗中的应用价值。方法随机选取2020年1月—2023年4月山东国欣颐养集团枣庄医院收治的脑动脉瘤患者50例为研究对象,根据就诊时间先后分为对照组(27例给予开颅夹闭术治疗)、观察组(23例给予血管内介入栓塞术治疗)。记录两组切口长度、手术时间、住院时间以及治疗前后血清指标,随访3个月后比较两组的疗效与并发症发生情况。结果观察组切口长度、手术时间与住院时间均短于对照组,差异有统计学意义(P均<0.05)。治疗后,两组血清指标水平均有改善,且观察组血管内皮生长因子、血清核因子-κB、可溶性细胞间黏附分子-1水平均低于对照组,差异有统计学意义(P均<0.05)。观察组有效率为95.65%,高于对照组的74.07%,并发症发生率为8.70%,低于对照组的33.33%,差异有统计学意义(χ^(2)=4.303、4.393,P均<0.05)。结论予以脑动脉瘤患者血管内介入栓塞术治疗不仅创伤小,且对血清指标的改善效果更好,有利于早期康复,同时治疗安全性更理想。

Objective To explore the application value of interventional embolization in the clinical treatment of cerebral aneurysm.Methods 50 patients with cerebral aneurysms admitted to Shandong Guoxin Yiyan Group Zaozhuang Hospital from January 2020 to April 2023 were randomly selected as the study objects.According to the time of treatment,they were divided into control group(27 cases received craniotomy)and observation group(23 cases received intravascular interventional embolization).Incision length,operation time,hospital stay and serum indexes before and after treatment were recorded in the two groups.The efficacy and complications of the two groups were compared after 3 months of follow-up.Results The incision length,operation time and hospital stay in the observation group were shorter than those in the control group,and the differences were statistically significant(all P<0.05).After treatment,the levels of serum indexes in both groups were improved,and the levels of vascular endothelial growth factor,serum nuclear factor-κB and soluble intercellular adhesion molecule-1 in the observation group were lower than those in the control group,the differences were statistically significant(all P<0.05).The effective rate of the observation group was 95.65%,which was higher than that of the control group(74.07%),and the complication rate was 8.70%,which was lower than that of the control group(33.33%),and the differences were statistically significant(χ^(2)=4.303,4.393,both P<0.05).Conclusion Endovascular embolization for cerebral aneurysm patients not only has less trauma,but also has better improvement effect on serum indexes,which is conducive to early rehabilitation.At the same time,the treatment safety is more ideal.