改良加盖岛状皮瓣与尿道板纵切卷管尿道成形术治疗小儿尿道下裂的效果及预后影响因素分析

Effect and prognostic factors of OIF and TIP in children with hypospadias

目的探讨改良加盖岛状皮瓣(OIF)与尿道板纵切卷管尿道成形术(TIP)治疗小儿尿道下裂的疗效,分析预后影响的独立因素。方法2013年2月~2021年2月间收治的尿道下裂患儿164例,根据手术方式分为两组,TIP组82例,采用TIP治疗;OIF组82例,采用OIF治疗。比较两组治疗效果。根据愈后情况分为两组,即预后良好组(手术治愈,151例),预后不佳组(手术未治愈,13例),采用多因素Logistic回归分析影响患儿预后独立因素。结果OIF组手术治愈率为96.34%,高于TIP组的87.8%,术后并发症发生率为7.32%,低于TIP组的23.17%,差异有统计学意义(P<0.05)。TIP组手术时间为(95.95±12.35)分钟,短于OIF组,差异有统计学意义(P<0.05)。多因素Logistic回归分析表明,尿道下裂分度、Barcat分型是影响尿道下裂患儿预后因素,术前阴茎下弯程度、阴茎头宽度、手术方式属于可疑因素。结论OIF与TIP治疗小儿尿道下裂均具有良好疗效,其中OIF手术成功率更高,TIP手术时间更短。影响预后的独立因素为术前尿道下裂分度、Barcat分型,本次手术方式并不作为预后独立影响因素。

Objective To explore the efficacy and prognostic independent factors of modified island flap(OIF)and urethroplasty(tip)in the treatment of hypospadias in children.Methods The 164 children with hypospadias analyzed retrospectively were treated from February,2013 to February,2021.They were divided into two groups according to the operation method.82 patients in tip group were treated with tip and 82 patients in OIF group were treated with OIF.The treatment effects of the two groups were compared.Then they were divided into two groups according to the cure condition,namely,the good prognosis group(cured by operation,151 case)and the poor prognosis group(not cured by operation,13 case).Independent factors affecting the prognosis of children were analyzed by binary logistic regression.Results The cure rate of OIF group was 96.34%,which was higher than that of the tip group(87.8%),and the incidence of postoperative complications in OIF group was 7.32%,which was lower than that of the tip group(23.17%,P<0.05).The operation time in tip group(95.95±12.35)min,which was shorter than that of the OIF group(P<0.05).At the same time,the binary logistic regression analysis showed that the degree of hypospadias and the classification of barcat were the prognostic factors of children with hypospadias.The degree of penis bending,the width of penis head and the method of operation were suspicious factors.Conclusion OIF and tip have good effects in the treatment of hypospadias in children.OIF has a higher success rate,tip has a shorter operation time and fewer postoperative complications.However,the independent factors affecting the prognosis of children are preoperative hypospadias classification and barcat classification.This operation method is not an independent factor affecting the prognosis.