摘要
子宫颈病变的阴道菌种结构复杂性、多样性明显,阴道乳杆菌种类和丰度对阴道微生态平衡起着重要作用,惰性乳杆菌则反之;犬布鲁氏菌、戴阿李斯特琥珀酸纤毛杆菌、阴道加德纳菌和短普雷沃菌与人类乳头瘤病毒(Human Papillomavirus,HPV)感染致宫颈病变密切相关。维持阴道微生态平衡可有效地消除病毒,防止宫颈癌的发生。本研究就阴道微生态的改变对HPV致宫颈病变的影响进行探讨。
The complexity and diversity of vaginal bacterial structures in cervical lesions are obvious,and the species and abundance of Lactobacillus vaginalis play an important role in the vaginal microecological balance,while inert Lactobacillus inertia is vice versa.Brucella canis,Ciliobacterium dyeriensis succinate,Gardnerella vaginalis and Prevotella short are closely associated with human papillomavirus(HPV)infection causing cervical lesions.Maintaining vaginal microecological balance can effectively eliminate the virus and prevent cervical cancer.In this study,we investigated the effect of vaginal microecological changes on HPV-caused cervical lesions.
作者
田丽君
石继海
余艳琴
于涵
贾喜梅
TIAN Lijun;SHI Jihai;YU Yanqin;YU Han;JIA Ximei(Department of Obstetrics and Gynecology,the First Affiliated Hospital of Baotou Medical College,Baotou,Inner Mongolia Autonomous Region,014010 China;Epidemiology Research Center,the First Affiliated Hospital of Baotou Medical College,Baotou,Inner Mongolia Autonomous Region,014010 China)
出处
《系统医学》
2024年第1期187-190,共4页
Systems Medicine
基金
2022年度自治区卫生健康科技计划项目(202202243)
包头市卫生健康科技计划项目(wsjkkj002)。
关键词
高通量测序
人乳头瘤病毒
阴道微生态
宫颈病变
High-throughput sequencing
Human papillomavirus
Vaginal microecology
Cervical lesions
