Construction of the Pkd1 gene knockout mouse model with polycystic kidney disease based on CRISPR/Cas9 technology

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摘要 Objective To establish a conditional knockout mouse model of polycystic kidney disease 1(Pkd1)gene based on CRISPR/Cas9 and Cre-loxP gene editing technology,and to provide an animal model for in-depth research on the role of Pkd1 gene in the development of polycystic kidney disease.

作者马广强 MA Guangqiang(Pathogen Biol&Immunol Discipline Group,CM Coll,Jiangxi CM Univ,Nanchang 330004)

机构地区 Pathogen Biol&Immunol Discipline Group

出处《China Medical Abstracts(Internal Medicine)》 2023年第4期227-228,共2页 中国医学文摘（内科学分册（英文版）

关键词 CRISPR/Cas9 KIDNEY POLYCYSTIC

分类号 R692 [医药卫生—泌尿科学] R-332 [医药卫生]

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China Medical Abstracts(Internal Medicine)

2023年第4期

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Construction of the Pkd1 gene knockout mouse model with polycystic kidney disease based on CRISPR/Cas9 technology

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