摘要
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)was reported at the end of 2019 as a worldwide health concern causing a pandemic of unusual viral pneumonia and many other organ damages,which was defined by the World Health Organization as coronavirus disease 2019(COVID-19).The pandemic is considered a significant threat to global public health till now.In this review,we have summarized the lessons learnt during the emergence and spread of SARS-CoV-2,including its prototype and variants.The overall clinical features of variants of concern(VOC),heterogeneity in the clinical manifestations,radiology and pathology of COVID-19 patients are also discussed,along with advances in therapeutic agents.
基金
supported by Shanghai Municipal Key Clinical Specialty(No.shslczdzk02202)
Shanghai Top-Priority Clinical Key Disciplines Construction Project(No.2017ZZ02014)
Shanghai Key Laboratory of Emergency Prevention,Diagnosis
Treatment of Respiratory Infectious Diseases(No.20dz2261100)
Cultivation Project of Shanghai Major Infectious Disease Research Base(No.20dz2210500).
