艾滋病患者症状群的研究进展

Research progress on symptom clusters in AIDS patients

随着抗逆转录酶治疗(ART)的广泛应用,人类免疫缺陷病毒(HIV)感染已从致死性疾病转变成可控的慢性疾病,但在治疗过程中艾滋病患者会经历多种症状,这些症状并不是孤立存在,而是协同作用,共同形成症状群,从而影响患者的预后和生活质量。目前对HIV症状群的综述鲜有报道,本文对症状群的定义,艾滋病患者症状群的分类情况、常用评估工具、研究方法及干预进展进行综述,以期为艾滋病患者的症状群管理提供理论依据。

Objective With the widespread use of antiretroviral therapy(ART),human immunodeficiency virus(HIV)infection has been transformed from a lethal disease to a manageable chronic disease.However,during the course of treatment,HIV/acquired immune deficiency syndrome(AIDS)patients experience a variety of symptoms,which do not exist in isolation,but synergistically to form symptom clusters,thus affecting patients'prognosis and quality of life.At present,there are few reports on the review of HIV symptom clusters.This paper reviewed the definition of symptom clusters,the classification of symptom clusters in HIV/AIDS patients,common assessment tools,research methods,and intervention progress,in order to provides a theoretical basis for the management of symptom clusters in HIV/AIDS patients.