摘要
目的基于文献计量学分析中医药防治阿尔茨海默病的研究热点及发展趋势。方法检索中国知识资源总库(CNKI)建库至2022年12月31日中医药防治阿尔茨海默病相关文献,应用CiteSpace6.1.R3和VOSviewer1.6.18对发文量、发文机构、作者、关键词等内容进行可视化分析。结果共纳入文献1672篇,年发文量呈波动上升趋势,《中华中医药学刊》发文量最高,孙国杰-杜艳军团队贡献显著,北京中医药大学为本研究领域核心机构。网络药理学、作用机制、盐酸多奈哌齐、认知、肠道菌群为近5年关注度较高的热点。结论中医药防治阿尔茨海默病研究机构间的合作网络初步形成,跨区域合作亟待加强;现阶段研究主要集中于机制研究和网络药理学研究,临床研究较少。对于作用机制的进一步探讨、临床疗效观察可能成为未来的发展趋势。
Objective To analyse the research trends and hotspots of TCM for the prevention and treatment of Alzheimer disease from a bibliometric perspective.Methods CNKI was used as the data source to retrieve the literature related to TCM for the prevention and treatment of Alzheimer disease from the establishment of the database to Dec.31,2022.CiteSpace 6.1.R3 and VOSviewer 1.6.18 were applied to visualize and analyze the volume of articles,issuing institutions,authors,keywords,etc.Results 1672 articles were included.The number of articles issued showed a fluctuating upward trend.The Journal of Chinese Traditional Medicine was the journal with the highest publication volume.The contribution of the Sun Guojie-Du Yanjun team was remarkable,and Beijing University of Chinese Medicine was the core institution of TCM for the prevention and treatment for Alzheimer disease.The hotspots with high attention in the past 5 years were network pharmacology,mechanism of action,donepezil hydrochloride,cognition,and intestinal flora.Conclusion At this stage,inter-institutional cooperation networks have been formed initially,and cross-regional cooperation needs to be strengthened.Research is mainly focused on mechanism research and network pharmacology research,with few clinical researches.Further exploration of the mechanism of action and clinical efficacy observation may become the future development trend.
作者
徐帆
吴林纳
徐志杰
王东军
李桂平
XU Fan;WU Linna;XU Zhijie;WANG Dongjun;LI Guiping(First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300381,China;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Tianjin 300381,China;North China University of Science and Technology,Tangshan 063210,China)
出处
《中国中医药图书情报杂志》
2024年第2期114-119,共6页
Chinese Journal of Library and Information Science for Traditional Chinese Medicine
基金
国家中医药管理局“全国中医临床特色技术传承骨干人才项目”(498022-3)
天津市十三五创新团队建设项目(TD13-5049)
天津市科技计划-中国工程院院地合作项目(21ZLGCGX00030)。
