柴芩温胆汤加减治疗糖尿病胃轻瘫的效果观察

Observation on the Effectiveness of Chaiqin Wendan Decoction Plus Re⁃duction in the Treatment of Diabetic Gastroparesis

目的 分析柴芩温胆汤加减治疗痰热瘀阻型糖尿病胃轻瘫患者的临床效果。方法 选择2021年6月—2022年12月福州市长乐区中医院治疗的90例痰热瘀阻型糖尿病胃轻瘫患者为研究对象,将患者按照入院时间的先后顺序均分为对照组和研究组,各45例。对照组给予多潘立酮片治疗,研究组联合柴芩温胆汤加减治疗,比较两组患者中医证候积分、临床疗效、血糖水平、胃肠功能、胃排空时间、胃排空率。结果 与对照组比较,研究组治疗后各项中医证候积分更低,临床疗效更高,各项血糖指标水平更低,胃泌素、胃动素水平更高,胆囊收缩素水平更低,胃排空时间更短,胃排空率更大,差异有统计学意义(P均<0.05)。结论 痰热瘀阻型糖尿病胃轻瘫患者在常规西药治疗基础上应用柴芩温胆汤治疗的效果更确切,不仅可以减轻患者症状,改善患者血糖水平与胃肠功能,还可以缩短胃排空时间,增大胃排空率。

Objective To analyze the clinical effect of Chaiqin Wendan decoction plus reduction in treating patients with phlegm-heat stasis type diabetic gastroparesis.Methods A total of 90 patients with phlegm-heat stasis diabetic gastroparesis treated in Fuzhou Changle District Hospital of Traditional Chinese Medicine from June 2021 to Decem-ber 2022 were selected as the study subjects,and the patients were divided into control group and study group accord-ing to the order of admission time,with 45 cases in each group.The control group was treated with domperidone tab-lets,and the study group added Chaiqinwendan Decoction for treatment.The traditional chinese medicine syndrome score,clinical efficacy,blood glucose level,gastrointestinal function,gastric empting time and gastric empting rate were compared between the two groups.Results Compared with the control group,the study group after treatment had lower scores of traditional chinese medicine syndrome,higher clinical efficacy,lower levels of blood glucose indexes,higher levels of gastrin and motilin,lower levels of cholecystokinin,shorter gastric emptying time and greater gastric emptying rate,the differences were statistically significant(all P<0.05).Conclusion The effect of the application of Chaiqin Wendan decoction on the basis of conventional Western medicine treatment in patients with phlegm-heat sta-sis type diabetes mellitus gastroparesis is more accurate,which can not only alleviate the symptoms of the patients,im-prove the patients'blood glucose level and gastrointestinal function,but also shorten the time of gastric emptying,and increase the rate of gastric emptying.