功劳木外洗液对非哺乳期乳腺炎溃后期患者的效果

Effect of Gonglaomu external lotion in treatment of patients with non-lactating mastitis in later stage of ulceration

目的 探究功劳木外洗液对非哺乳期乳腺炎(NMP)溃后期患者创面愈合、窦道深度及垂体泌乳素即催乳素(PRL)的影响。方法 选取NMP溃后期患者140例,分为观察组和对照组,每组70例。采用Image J软件计算患者治疗前后的创面面积并统计渗液量,采用银质探针测量治疗前后患者的窦道深度,采用化学电发光法检测治疗前后患者PRL水平;比较2组疗效、创面面积、渗液量、窦道深度、PRL水平的变化。结果 观察组治疗总有效率优于对照组,治疗后观察组的创面面积和渗液量均低于对照组,治疗后观察组的窦道深度低于对照组,治疗后2组PRL均降低,且观察组的PRL低于对照组,观察组复发率低于对照组,差异有统计学意义(P<0.05)。结论 功劳木外洗液可以有效改善NMP溃后期患者创面愈合情况、窦道深度及PRL水平。

Objective To investigate the effects of Gonglaomu external lotion on wound healing,sinus depth and pituitary prolactin(PRL) in patients with non-lactating mastitis(NMP) in the late stage of ulceration.Methods A total of 140 patients with NMP in the late stage of ulceration were selected and divided into observation group(n=70) and control group(n=70).Image J software was used to calculate the wound area before and after treatment,and the amount of exudation was recorded;the sinus depth was measured with silver probe before and after treatment;the level of PRL was detected by chemiluminescence before and after treatment;the efficacy,wound area,exudate volume,sinus depth and PRL level were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group;after treatment,the wound area and exudation volume of the observation group were lower than those of the control group;after treatment,the sinus depth in the observation group was lower than that in the control group;the PRL in both groups decreased after treatment,and the PRL of the observation group was lower than that of the control group;the recurrence rate in the observation group was lower than that in the control group;all the between-group differences mentioned above were statistically significant(P<0.05).Conclusion Gonglaomu external lotion can effectively improve condition of wound healing,sinus depth and PRL level in patients with NMP in the late stage of ulceration.