酒石酸美托洛尔联合银杏达莫注射液治疗冠心病心绞痛的效果分析

Analysis on Effect of Metoprolol Tartrate Combined with Ginkgo Leaf Extract and Dipyridamole Injection in Treatment of Coronary Heart Disease with Angina Pectoris

目的:分析酒石酸美托洛尔联合银杏达莫注射液治疗冠心病心绞痛(CHD-AP)的效果。方法:选取2020年1月—2022年1月靖江市新桥镇中心卫生院收治的CHD-AP患者80例作为研究对象,依据随机数字表法分为两组,各40例。两组均给予常规治疗,对照组给予酒石酸美托洛尔片治疗,观察组在对照组基础上应用银杏达莫注射液。比较两组治疗效果。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P=0.042)。治疗前,两组心绞痛发作频率、持续时间比较,差异无统计学意义(P>0.05);治疗后,两组心绞痛发作频率低于治疗前,且观察组低于对照组,两组心绞痛持续时间短于治疗前,且观察组短于对照组,差异有统计学意义(P<0.05)。治疗前,两组胸痛、胸闷、心悸评分比较,差异无统计学意义(P>0.05);治疗后,两组胸痛、胸闷、心悸评分低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P=0.456)。结论:酒石酸美托洛尔联合银杏达莫注射液治疗CHD-AP的效果较好,可降低患者心绞痛发作频率,缩短心绞痛持续时间,减轻临床症状,且不会增加不良反应,安全性高。

Objective:To analyze the effect of Metoprolol Tartrate combined with Ginkgo Leaf Extract and Dipyridamole Injection in treatment of coronary heart disease with angina pectoris(CHD-AP).Methods:A total of 80 CHD-AP patients admitted to Jingjiang Xinqiao Town Central Health Center from January 2020 to January 2022 were selected as the study subjects.They were divided into two groups according to random number table method,with 40 cases in each group.Both groups received conventional treatment,the control group was treated with Metoprolol Tartrate,and the observation group was treated with Ginkgo Leaf Extract and Dipyridamole Injection on the basis of control group.The treatment effect was compared between two groups.Results:The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P=0.042).Before treatment,there was no significant difference in the frequency of angina pectoris attacks and duration of angina pectoris between the two groups(P>0.05);After treatment,the frequency of angina pectoris attacks in the two groups was lower than that before treatment,and the frequency in the observation group was lower than that in the control group,while the duration of angina pectoris in the two groups was shorter than that before treatment,and the duration in the observation group was shorter than that in the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in the scores of chest pain,chest tightness and palpitation between the two groups(P>0.05);After treatment,the scores of chest pain,chest tightness and palpitations in the two groups were lower than those before treatment,and the scores in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P=0.456).Conclusion:Metoprolol Tartrate combined with Ginkgo Leaf Extract and Dipyridamole Injection has good effects in treatment of CHD-AP,and can reduce the frequency of angina pectoris attacks,shorten the duration of angina pectoris,relieve clinical symptoms,and will not increase adverse reactions,and have high safety.