黄连温胆汤加减治疗冠心病PCI术后合并焦虑状态的临床效果

Clinical Effect of Modified Huanglian Wendan Decoction in Treatment of Anxiety State After PCI for Coronary Heart Disease

目的:观察黄连温胆汤加减治疗冠心病经皮冠状动脉介入治疗(PCI)术后合并焦虑状态的临床效果。方法:选取2021年10月—2023年10月北京市中关村医院收治的冠心病PCI术后合并焦虑状态患者60例作为研究对象,依据随机数字表法分为两组,各30例。对照组给予心理指导联合常规药物治疗,观察组在对照组基础上给予黄连温胆汤加减治疗。比较两组焦虑状态、中医证候评分、治疗效果、不良反应发生情况。结果:治疗前,两组焦虑评分比较,差异无统计学意义(P>0.05);治疗后,两组焦虑评分低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗前,两组中医证候评分比较,差异无统计学意义(P>0.05);治疗后,两组中医证候评分低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率高于对照组,差异有统计学意义(P<0.001)。两组治疗过程中均未发生腹泻、恶心呕吐。结论:黄连温胆汤加减治疗冠心病PCI术后合并焦虑状态的效果较好,可改善患者焦虑情况以及临床症状,且安全性较高。

Objective:To observe the clinical effect of modified Huanglian Wendan Decoction in treating anxiety state after percutaneous coronary intervention(PCI)for coronary heart disease.Methods:A total of 60 patients with anxiety after PCI for coronary heart disease admitted to Beijing Zhongguancun Hospital from October 2021 to October 2023 were selected as the study subjects.They were divided into two groups according to random number table method,with 30 cases in each group.The control group was given psychological guidance combined with routine drug treatment.The observation group was treated with modified Huanglian Wendan Decoction on the basis of the control group.The anxiety state,traditional Chinese medicine syndrome scores,treatment effects and occurrence of adverse reactions were compared between two groups.Results:There was no significant difference in anxiety scores between the two groups(P>0.05);After treatment,the anxiety scores in the two groups were lower than those before treatment,and the scores in the observation group were lower than those in the control group,with a statistically significant difference(P<0.05).Before treatment,there was no significant difference in traditional Chinese medicine syndrome scores between the two groups(P>0.05);After treatment,the traditional Chinese medicine syndrome scores in the two groups were lower than those before treatment,and the scores in the observation group were lower than those in the control group,with a statistically significant difference(P<0.05).The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.001).There was no diarrhea,nausea and vomiting in the two groups during treatment.Conclusion:The modified Huanglian Wendan Decoction has good effect in treating anxiety state after PCI for coronary heart disease,and can ameliorate the anxiety and clinical symptoms of patients,with high safety.