不同分期慢性肾病患者的焦虑抑郁情况

The status of anxiety and depression in patients with different stages of chronic kidney disease

目的研究不同分期慢性肾脏病患者的抑郁、焦虑状态。方法选择2021年1月~2023年1月期间我院收治的慢性肾脏病患者100例为研究对象,以肾小球滤过率为基本依据,将其分为两组,分别为慢性肾脏病(chronic kidney disease,CKD)5期组和CKD1-4期组,然后运用抑郁自评量表(Self-rating Depression Scale,SDS)和焦虑自评量表(Self-rating anxiety scale,SAS)评估其抑郁和焦虑状态。结果本组的100例患者中,63例为1-4期,占63.0%,37例为CKD5期,占37%;与国内正常人群相比,CKD患者的SDS和SAS评分均较高,比较有统计学差异(P<0.05);CKD5期组的SDS评分明显高于CKD1-4期组(P<0.05);但是两组的SAS评分对比差异无统计学意义(P>0.05);同时,将有无抑郁、焦虑症状作为因变量,对Logistic回归模型进行构建,结果发现CKD患者合并抑郁、焦虑症状与年龄和疾病分期有关(P<0.05)。结论慢性肾病患者往往存在不同程度的抑郁、焦虑情况,并且随着年龄的增加和肾功能下降,抑郁、焦虑程度加重,所以要加强心理干预,减轻负面情绪,改善预后。

Objective To study and analyze the depression and anxiety status of patients with different stages of chronic kidney disease.Method 100 patients with chronic kidney disease admitted to our hospital from January 2021 to January 2023 were selected as the study objects.Based on the glomerular filtration rate,they were divided into two groups:Chronic kidney disease(CKD)stage 5 group and CKD stage 1-4 group.Then,the Self-rating Depres-sion Scale(SDS)and Self-rating anxiety scale(SAS)were used to assess their depression and anxiety status.Results Among 100 patients,63 cases were CDK1-4,accounting for 63.0%,37 cases were CKD5,accounting for 37%.The SDS and SAS scores of CKD patients were higher than those of normal population in China(P<0.05).The SDS score of CKD5 group was significantly higher than that of CKD1-4 group(P<0.05).However,there was no significant difference in SAS scores between the two groups(P>0.05).At the same time,the presence or absence of depres-sion and anxiety symptoms were used as dependent variables to construct the Logistic regression model,and the results showed that the symptoms of depression and anxiety in CKD patients were related to age and disease stage(P<0.05).Conclusion Patients with chronic kidney disease often have different depression and anxiety conditions,and with the increase of age and decline of kidney function,depression and anxiety degree is aggravated,so it is necessary to strengthen psychological intervention,reduce negative emotions,help to improve the prognosis of patients.