药物联合心理治疗对耳鸣患者伴发焦虑抑郁的效果

The effect of medcine combined with psychological intervention in tinnitus patients with anxiety and depression

目的探讨药物联合心理治疗对耳鸣患者伴发焦虑抑郁的效果。方法2020年4月~2022年12月本院收治的118例耳鸣后焦虑、抑郁患者纳入研究,以序贯平衡法分组,一组接受心理干预(纳入对照),二组在其基础上接受帕罗西汀+枸橼酸坦度螺酮片治疗(纳入观察)。对比118例患者的临床疗效,并分析干预后患者听阈、心理状态、睡眠质量变化。结果观察组59例患者经药物联合心理干预治疗后临床疗效高于对照组(P<0.05);观察组睡眠状况自评量表(Self-Rating Scale of Sleep,SRSS)评分低于对照组(P<0.05);观察组汉密顿抑郁量表-17(Hamilton Depression Scale-17,HAMD-17)、汉密顿焦虑量表(Hamilton Anxiety Scale,HAMA)评分低于对照组(P<0.05);观察组听阈低于对照组(P<0.05)。结论在耳鸣后焦虑、抑郁患者的治疗中选择药物联合心理干预的方案,既可提高整体治疗效果,同时可改善其焦虑、抑郁状态,减轻疾病对其睡眠质量的影响。

Objective To explore The effect of medcine combined with psychological intervention in tinnitus patients with anxiety and depression.Methods The data of 118 patients with post tinnitus anxiety and depression ad-mitted to our hospital from April 2020 to December 2022 were analyzed.The patients were divided into two groups by sequential balance method.The first group received psychological intervention(included in the control group),and the second group received Paroxetine+Tandospirone citrate tablets on the basis of the first group(included in the observa-tion group).Compare the clinical efficacy of 118 patients and analyze the changes in their hearing threshold,psycho-logical state,and sleep quality after intervention.Results The clinical efficacy of 59 patients in the observation group after medication combined with psychological intervention treatment was higher than that in the control group(P<0.05).The Self Rating Scale of Sleep(SRSS)score of the observation group was lower than that of the control group(P<0.05).The Hamilton Depression Scale-17(HAMD-17)and Hamilton Anxiety Scale(HAMA)scores in the observation group were lower than those in the control group(P<0.05).The hearing threshold of the observation group was lower than that of the control group(P<0.05).Conclusion The combination of medication and psychological intervention in the treatment of patients with anxiety and depression after tinnitus can not only improve their overall treatment effect,but also improve their anxiety and depression status,reduce the impact of the disease on their sleep quality.