宫腔镜冷刀技术在有生育要求子宫黏膜下肌瘤病人中的应用价值

Application value of hysteroscopic cold knife technique in patients with submucous myoma of uterus and fertility requirements

目的:探究宫腔镜冷刀技术在有生育要求子宫黏膜下肌瘤病人中的应用价值。方法:选择90例子宫黏膜下肌瘤病人作为研究对象,其中通过宫腔镜冷刀技术进行治疗的病人45例作为观察组,通过宫腔镜电切术进行治疗的病人45例作为对照组;对比2组病人术中出血量、手术时间、并发症情况、术前及术后第1天炎症指标(白细胞介素-6、C反应蛋白)、术后3个月宫腔粘连情况及子宫内膜厚度、术后12个月妊娠情况等差异。结果:与对照组比较,观察组手术时间短、并发症发生率低、术后炎症指标低、术后子宫内膜修复状况良好且妊娠率高,差异均有统计学意义(P<0.05~P<0.01)。结论:宫腔镜冷刀系统在有生育要求子宫黏膜下肌瘤病人的治疗中,具有手术时间短、并发症少、宫腔粘连发生率低、对子宫内膜损伤小和术后妊娠率高等优势,是一种值得普及的微创术式。

Objective:To explore the application value of hysteroscopic cold knife technique in patients with uterine submucosal myoma of uterus and fertility requirements.Methods:A total of 90 patients with submucosal myoma of the uterus were selected as the study subjects,with 45 patients treated with hysteroscopic cold knife technique as the observation group and 45 patients treated with hysteroscopic electrocautery as the control group.The differences in intraoperative bleeding volume,surgical time,complications,inflammatory indicators(interleukin-6,C reactive protein)before and on the first day after surgery,intrauterine adhesions and endometrial thickness at 3 months after surgery,and pregnancy at 12 months after surgery between the two groups of patients were compared.Results:Compared with the control group,the observation group had shorter surgical time,lower incidence of complications,lower postoperative inflammatory indicators,good endometrial repair status and higher pregnancy rate(P<0.05 to P<0.01).Conclusions:The hysteroscopic cold knife technique has the advantages of short surgical time,fewer complications,low incidence of uterine adhesions,minimal damage to the endometrium and high postoperative pregnancy rate in the treatment of submucosal myoma of uterus in patients with fertility requirements,which is a minimally invasive surgery worthy of popularization.