妊娠期血清尿酸和促甲状腺激素与妊娠期高血压疾病的关系研究

Study on the Relationship between Pregnancy Serum Uric Acid and Thyroid-stimulating Hormone and Hypertensive Disorders of Pregnancy

妊娠期高血压疾病是指妊娠和高血压并存的妊娠合并症,可对孕产妇及围生儿的健康造成严重影响。很多学者对妊娠期高血压疾病患者进行回顾性分析研究,发现血清尿酸及促甲状腺激素(TSH)水平的变化和妊娠期高血压疾病的发生进展有紧密相关性。本文通过对血清尿酸、TSH与妊娠期高血压疾病关系的最新研究进行综述,发现血清尿酸及TSH水平在妊娠期高血压疾病患者中显著增加,且血清尿酸与甲状腺功能减退之间有紧密联系,它们在妊娠期共同影响血压的变化,提高了妊娠期高血压疾病发生的风险。

Hypertensive disorders of pregnancy is a pregnancy comorbidity of pregnancy and hypertension coexist,which can seriously affect the health of maternity and perinatal children.Many scholars have retrospectively analyzed and studied the patients with hypertensive disorders of pregnancy,and found that the changes of serum uric acid and thyroid-stimulating hormone(TSH)levels are closely related to the occurrence and progression of hypertensive disorders of pregnancy.In this paper,the latest research on the relationship between serum uric acid,TSH and hypertensive disorders of pregnancy is reviewed,and it is found that serum uric acid and TSH levels increase significantly in patients with hypertensive disorders of pregnancy,and there is a close relationship between serum uric acid and hypothyroidism,which jointly affect the changes of blood pressure during pregnancy and increase the risk of hypertensive disorders of pregnancy.