阿托品在近视防控中的临床应用研究进展

Research Progress of Atropine in the Prevention and Control of Myopia

随着近视率的持续上升,近视防控的研究已成为眼科研究领域的热点。大量临床研究实验表明阿托品在儿童近视防控方面具有显著的临床意义。阿托品滴眼液是经循证医学验证能有效延缓近视进展的药物,但目前其作用机制还不十分明确,药物疗效、不良反应等也存在较大的个体差异。通过研究总结近年来阿托品的相关临床实验成果,对阿托品的近视防控作用机制、药物浓度疗效、不良反应等进行归纳总结。

With the continuous rise of myopia,the prevention and control of myopia has become a hot spot in the field of ophthalmology.A large number of clinical studies and experiments have confirmed that atropine has significant clinical significance in the prevention and control of myopia in children.Atropine eye drops are still the only drugs that can effectively delay the progression of myopia verified by evidence-based medicine.However,the mechanism of action of atropine is not very clear,and there are large individual differences in drug efficacy and adverse reactions.The related clinical experimental studies of atropine in recent years was combined,and the mechanism of myopia prevention and control of atropine,drug concentration efficacy,adverse reactions and so on were summarized.